Acetylsalicylic Acid and Eflornithine in Treating Patients at High Risk for Colorectal Cancer
Completed
National Cancer Institute (NCI)
Phase 2
2009-08-20
This phase II trial is studying how well giving acetylsalicylic acid together with
eflornithine works in treating patients at high risk for colorectal cancer. Chemoprevention
is the use of certain drugs to keep cancer from forming. The use of acetylsalicylic acid and
eflornithine may prevent colorectal cancer.
Intermittent or Continuous Acetylsalicylic Acid and Gene Expression in the Nasal Tissue of Current Smokers
Completed
National Cancer Institute (NCI)
Phase 2
2014-06-01
This randomized phase II trial studies the safety and effects of acetylsalicylic acid
(aspirin) taken continuously or intermittently on gene expression in the nasal tissue of
current smokers. Smokers are at increased risk of developing lung cancer. Acetylsalicylic
acid may be useful in preventing lung cancer.
Acetylsalicylic Acid Compared to Placebo in Treating High-Risk Patients With Subsolid Lung Nodules
Completed
National Cancer Institute (NCI)
Phase 2
2014-11-21
This randomized phase II trial studies acetylsalicylic acid compared to placebo in treating
high-risk patients with subsolid lung nodules. A nodule is a growth or lump that may be
malignant (cancer) or benign (not cancer). Chemoprevention is the use of drugs to keep cancer
from forming or coming back. The use of acetylsalicylic acid may keep cancer from forming in
patients with subsolid lung nodules.
Aspirin and Zileuton and Biomarker Expression in Nasal Tissue of Current Smokers
Completed
National Cancer Institute (NCI)
Phase 2
2016-01-13
This randomized phase II trial studies the effects of aspirin and zileuton on genes related
to tobacco use in current smokers. Aspirin and zileuton may interfere with genes related to
tobacco use and may be useful in preventing lung cancer in current smokers.
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