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Generated: June 20, 2019

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CLINICAL TRIALS PROFILE FOR MAGNESIUM CHLORIDE; SODIUM BICARBONATE; SODIUM CHLORIDE

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Clinical Trials for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride

Trial ID Title Status Sponsor Phase Summary
NCT00045799 Safety & Efficacy of Omeprazole Sodium Bicarbonate for the Prevention of Upper GI Bleeding in the Critically Ill Completed Valeant Pharmaceuticals International, Inc. Phase 3 Critically ill patients are at an increased risk of having upper gastrointestinal (GI) bleeding due to stress related mucosal damage. Cimetidine, delivered continuously through intravenous infusion, is the only drug that the FDA has approved for the prevention of upper GI bleeding in critically ill patients. The present trial is intended to assess the safety and efficacy of an omeprazole sodium bicarbonate immediate-release suspension in this indication.
NCT00130598 PROVOCATION Trial - PROphylactic intraVenOus Hydration for Contrast Agent Toxicity PreventION Completed Swiss National Science Foundation Phase 2/Phase 3 Contrast nephropathy (CN) remains a common complication of radiographic procedures and an important cause of hospital-acquired acute renal failure. Only hydration with saline is uniformly accepted and used in clinical practice as a cornerstone for the prevention of CN. But the optimal preventive strategy for CN is not known. Sodium bicarbonate might be even more effective than hydration with sodium chloride for prophylaxis of CN. Therefore the aim of the study is to evaluate the efficacy of two regimens of sodium bicarbonate compared with a prolonged infusion of sodium chloride in the prevention of CN. Primary endpoint: Decrease in glomerular filtration rate (GFR) within 48 hours.
NCT00130598 PROVOCATION Trial - PROphylactic intraVenOus Hydration for Contrast Agent Toxicity PreventION Completed University Hospital, Basel, Switzerland Phase 2/Phase 3 Contrast nephropathy (CN) remains a common complication of radiographic procedures and an important cause of hospital-acquired acute renal failure. Only hydration with saline is uniformly accepted and used in clinical practice as a cornerstone for the prevention of CN. But the optimal preventive strategy for CN is not known. Sodium bicarbonate might be even more effective than hydration with sodium chloride for prophylaxis of CN. Therefore the aim of the study is to evaluate the efficacy of two regimens of sodium bicarbonate compared with a prolonged infusion of sodium chloride in the prevention of CN. Primary endpoint: Decrease in glomerular filtration rate (GFR) within 48 hours.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride

Condition Name

Condition Name for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride
Intervention Trials
Contrast Induced Nephropathy 14
Acute Kidney Injury 11
Chronic Kidney Disease 9
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Condition MeSH

Condition MeSH for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride
Intervention Trials
Kidney Diseases 37
Acute Kidney Injury 25
Renal Insufficiency 20
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Clinical Trial Locations for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride

Trials by Country

Trials by Country for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride
Location Trials
United States 136
Italy 19
Brazil 13
Australia 12
Canada 9
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Trials by US State

Trials by US State for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride
Location Trials
California 11
Missouri 8
North Carolina 8
New York 7
Florida 7
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Clinical Trial Progress for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride

Clinical Trial Phase

Clinical Trial Phase for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride
Clinical Trial Phase Trials
Phase 4 48
Phase 3 36
Phase 2/Phase 3 10
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Clinical Trial Status

Clinical Trial Status for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride
Clinical Trial Phase Trials
Completed 79
Recruiting 31
Not yet recruiting 23
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Clinical Trial Sponsors for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride

Sponsor Name

Sponsor Name for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride
Sponsor Trials
Bayer 5
Valeant Pharmaceuticals International, Inc. 5
Ospedale Misericordia e Dolce 5
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Sponsor Type

Sponsor Type for Magnesium Chloride; Sodium Bicarbonate; Sodium Chloride
Sponsor Trials
Other 200
Industry 42
NIH 6
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