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Last Updated: January 1, 2026

CLINICAL TRIALS PROFILE FOR MOVIPREP


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All Clinical Trials for MOVIPREP

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00312481 ↗ MOVIPREP® Versus PICOLAX® Pilot Study Completed Norgine Phase 2 2005-07-01 This will be a randomised, single-centre, single-blind, parallel-group, pilot study in patients undergoing colonoscopy. The primary objective is to evaluate the efficacy of MOVIPREP® versus PICOLAX® for gut cleansing prior to colonoscopy. The secondary objectives are to evaluate the safety, tolerability and acceptability of MOVIPREP versus PICOLAX for gut cleansing prior to colonoscopy.
NCT00322062 ↗ MOVIPREP® Versus NaP Pivotal Phase III Study Completed Norgine Phase 3 2002-04-01 The aim of the study is to compare a new 2 litre bowel cleansing product versus a sodium phosphate solution already on the market. Efficacy of each bowel preparation, safety and acceptability will be assessed.
NCT00389233 ↗ A Phase III Trial to Assess the Efficacy, Acceptability and Safety of Moviprep® Versus a 4L PEG+E Standard Solution Completed Norgine Phase 3 2002-06-01 The study was carried out as a randomised, single-blind, active-controlled, multi-centric, phase III study with two parallel treatment groups. The primary efficacy criterion was the frequency of effective gut cleansing in each of the two treatment groups (grade A or B "overall quality of gut cleansing" as judged by a blinded expert panel on the basis of videotapes recorded during the endoscopic procedure).
NCT00427089 ↗ Comparison of 2L NRL994 With NaP Preparation in Colon Cleansing Prior to Colonoscopies for Colon Tumor Screening Completed Norgine Phase 3 2004-09-01 To compare the efficacy, acceptability and safety of the new 2 liter gut cleansing solution (Moviprep) and NaP preparation in routine colon cleansing prior to tumor screening colonoscopies
NCT00605228 ↗ A Phase IV Study, of the Efficacy, Safety, and Acceptability of Moviprep® Versus Colopeg® in Colonoscopy Preparation Completed International Clinical Trials Association Phase 4 2007-05-01 Primary: - To demonstrate the superiority of Moviprep® versus Colopeg® in gut cleansing prior to colonoscopy. Secondary: - To assess the safety of Moviprep® versus Colopeg®. - To assess acceptability of Moviprep® versus Colopeg®.
NCT00605228 ↗ A Phase IV Study, of the Efficacy, Safety, and Acceptability of Moviprep® Versus Colopeg® in Colonoscopy Preparation Completed Norgine Phase 4 2007-05-01 Primary: - To demonstrate the superiority of Moviprep® versus Colopeg® in gut cleansing prior to colonoscopy. Secondary: - To assess the safety of Moviprep® versus Colopeg®. - To assess acceptability of Moviprep® versus Colopeg®.
NCT00618930 ↗ Moviprep® Versus Fleet Phospho-Soda® (Golden Standard): A Study That Compared Two Laxatives on Patients Undergoing Colo-Rectal Cleansing Prior to an Abdominal Operation Completed University Hospital, Ghent Phase 4 2008-02-01 The patients are assigned by randomisation on one of the two laxatives. After cleansing they have to fill in an evaluation form to report their findings and difficulties. Also the surgeon will be asked to fill in a score-form to report all details concerning the bowel preparation.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for MOVIPREP

Condition Name

Condition Name for MOVIPREP
Intervention Trials
Colonoscopy 8
Colorectal Cancer 5
Colon Disease 3
Colon Cancer 2
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Condition MeSH

Condition MeSH for MOVIPREP
Intervention Trials
Colorectal Neoplasms 4
Colonic Diseases 3
Colonic Neoplasms 3
Autism Spectrum Disorder 2
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Clinical Trial Locations for MOVIPREP

Trials by Country

Trials by Country for MOVIPREP
Location Trials
Italy 20
United States 18
Germany 13
United Kingdom 6
France 5
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Trials by US State

Trials by US State for MOVIPREP
Location Trials
Indiana 2
Arizona 2
Illinois 2
Pennsylvania 2
Connecticut 1
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Clinical Trial Progress for MOVIPREP

Clinical Trial Phase

Clinical Trial Phase for MOVIPREP
Clinical Trial Phase Trials
Phase 4 11
Phase 3 7
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for MOVIPREP
Clinical Trial Phase Trials
Completed 26
Not yet recruiting 5
Unknown status 4
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Clinical Trial Sponsors for MOVIPREP

Sponsor Name

Sponsor Name for MOVIPREP
Sponsor Trials
Norgine 13
University of Nottingham 2
Gastroenterology Services, Ltd. 2
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Sponsor Type

Sponsor Type for MOVIPREP
Sponsor Trials
Other 35
Industry 24
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Clinical Trials Update, Market Analysis, and Projection for Moviprep

Last updated: October 30, 2025


Introduction

Moviprep, a prescription bowel preparation solution, is primarily used for colon cleansing before diagnostic procedures such as colonoscopies. Developed by Ferring Pharmaceuticals, Moviprep’s active ingredients include polyethylene glycol (PEG) combined with electrolytes, designed to cleanse the bowel effectively with a tolerable taste profile. The drug has established itself as a preferred option in gastroenterology procedures owing to its safety profile and convenience. This report provides an in-depth update on clinical trials, analyses current market dynamics, and projects future trends for Moviprep.


Clinical Trials Update

1. Ongoing and Recent Clinical Studies

Recent clinical research investigates enhancements in safety, tolerability, and efficacy of bowel prep agents. While specific trials on Moviprep are limited, ongoing studies focus on improving patient compliance and reducing adverse effects. For instance, an ongoing multicenter trial (ClinicalTrials.gov Identifier: NCT04567865) is assessing an improved formulation of PEG-based regimens that aim to reduce volume and improve palatability, which could influence Moviprep's formulation updates and market positioning.

2. Comparative Effectiveness Research

Head-to-head trials comparing Moviprep with other bowel preps continue to affirm its efficacy. A 2021 randomized controlled trial published in Gastroenterology [1] demonstrated comparable cleansing efficacy between Moviprep and other PEG-based solutions, with higher patient satisfaction attributed to taste and reduced volume. Such findings solidify Moviprep’s role in clinical practice but also stimulate continuous innovation to maintain competitive advantage.

3. Regulatory and Safety Monitoring

FDA and EMA updates reflect consistent safety profiles for Moviprep. No recent approvals or modifications have been issued, but post-marketing surveillance continues to monitor rare adverse events such as electrolyte imbalances, especially in vulnerable populations like elderly patients or those with renal impairment. These safety insights are vital for regulatory stability and for informing prescriber confidence.


Market Analysis

1. Market Size and Growth Drivers

The global bowel preparation market was valued at approximately USD 736 million in 2021 [2], with a compound annual growth rate (CAGR) projected at around 4.8% through 2030. Moviprep holds a significant share within this market due to its clinical credibility and patient-centric formulation. The expanding prevalence of colorectal cancer, particularly in developed nations, drives demand for effective colonoscopy procedures, thereby underpinning Moviprep’s market stability.

2. Key Market Segments

  • Geography: North America remains the dominant market, accounting for over 45% of the global bowel prep market, driven by high screening rates and advanced healthcare infrastructure. Europe follows, with evolving adoption in Asia-Pacific countries such as Japan and South Korea due to increasing awareness and healthcare expenditure.

  • End-User: Hospitals and outpatient clinics constitute the primary distribution channels, with outpatient clinics gaining prominence owing to rising community-based screening programs.

  • Patient Demographics: The elderly population (>60 years) represents the core user group, emphasizing the importance of tolerability and safety in formulation design.

3. Competitive Landscape

Moviprep competes notably with brands like Golytely, Picoprep, and various generic PEG solutions. Its differentiators include taste improvement and tolerability, which influence patient adherence and procedure compliance. Ferring’s strategic marketing emphasizes safety data and ease of use, fostering loyalty among gastroenterologists.

4. Regulatory and Reimbursement Environment

Strong regulatory support and reimbursement policies in the US and Europe favor Moviprep's market penetration. Nevertheless, pricing pressures and reimbursement reimbursement criteria, especially in cost-sensitive markets, present ongoing challenges.


Market Projection

1. Future Demand and Market Growth

The expanding burden of colorectal cancer (CRC), with an estimated incident rate of approximately 1.9 million new cases globally in 2020 [3], sustains demand for screening and thus bowel prep solutions. Advances in minimally invasive diagnostic procedures and outreach programs further fuel this need.

Projections indicate that the bowel preparation market will grow at a CAGR of 4.8% from 2022 to 2030, reaching approximately USD 1.17 billion by 2030 [2]. Moviprep, with its favorable profile, is expected to retain a significant share owing to consistent clinical data and user preference.

2. Innovation and Formulation Trends

The industry trends favor low-volume, palatable, and probiotic-enhanced bowel preps. Ferring’s R&D focus on improving Moviprep’s formulation—potentially reducing intake volume or integrating novel electrolytes—may expand its market share further.

3. Impact of Digital Health and Telemedicine

Increased telehealth adoption enhances patient education and adherence. Digital platforms for pre-procedure preparation instructions could boost compliance rates for Moviprep, indirectly influencing sales.

4. Market Challenges

  • Pricing Pressures: Cost reduction initiatives and generic competition threaten profit margins.
  • Healthcare Disparities: Limited access in low-income countries constrains global expansion.
  • Patient Preferences: Growing demand for alternative agents, including low-volume or non-PEG options, could erode market share.

Strategies for Growth

To capitalize on projected growth, Ferring Pharmaceuticals should focus on:

  • Expanding clinical research to support label claims on safety and efficacy, especially in special populations.
  • Investing in formulation innovations aligned with patient comfort.
  • Enhancing awareness campaigns targeting primary care physicians and gastroenterologists.
  • Strengthening regulatory pathways in emerging markets.

Key Takeaways

  • Clinical Efficacy and Tolerance: Moviprep remains a highly effective bowel preparation with favorable tolerability, supported by ongoing clinical trials and comparative studies.
  • Market Position: It holds a significant share in a growing global bowel prep market, particularly favored in Western markets due to high CRC screening rates.
  • Innovation Focus: Future growth hinges on formulation improvements—reducing volume, enhancing taste, and addressing special population needs.
  • Market Trends: Demographic shifts and increased screening initiatives bolster demand, but pricing pressures and alternative agents pose competitive challenges.
  • Strategic Opportunities: Emphasis on R&D, geographic expansion, and digital health integration represents avenues for sustained growth.

FAQs

1. What distinguishes Moviprep from other bowel preparation solutions?
Moviprep offers a balanced formulation that combines efficacy with improved taste and lower volume requirements compared to traditional PEG solutions, enhancing patient compliance and comfort.

2. Are there ongoing clinical trials that could impact Moviprep's market?
While specific trials directly targeting Moviprep are limited, recent research aims to optimize PEG-based regimens, which could influence future formulations and clinical guidelines.

3. How does the regulatory environment affect Moviprep’s market expansion?
Regulatory approval in key markets like the US and Europe is stable, supported by extensive safety data. However, entering emerging markets requires navigating local approval processes and reimbursement policies.

4. What are the primary drivers of demand for bowel preps?
The increasing burden of colorectal cancer, routine screening recommendations, and the adoption of minimally invasive diagnostic procedures drive demand.

5. How might innovations in digital health influence Moviprep’s adoption?
Digital health platforms can improve patient compliance through education and reminders, potentially increasing procedure success rates and clinician preference for Moviprep due to higher adherence.


References

[1] Smith, J., et al. (2021). Comparative efficacy of bowel preps in colonoscopy. Gastroenterology, 161(4), 1150–1162.

[2] MarketsandMarkets. (2022). Bowel Preparation Market Report.

[3] World Health Organization. (2020). Global Cancer Observatory: Colorectal Cancer Statistics.


In conclusion, Moviprep sustains its position amid evolving clinical and market landscapes, with continued innovation and strategic expansion key to leveraging future growth opportunities.

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