Safety and Efficacy of Intravenous Magnesium Sulfate in Modulating Changes in Symptoms and Divalent Cation Levels Associated With Foscavir Therapy: A Phase IV Randomized, Double-Blind, Placebo-Controlled, Cross-Over, Pilot Study
Completed
Astra USA
Phase 4
1969-12-31
To determine whether acute ionized hypomagnesemia and hypocalcemia immediately following
foscarnet infusions can be lessened or eliminated by prior infusion of magnesium sulfate. To
determine whether reductions in ionized magnesium, ionized calcium, and parathyroid hormone
levels following foscarnet infusions are lessened by preinfusion of magnesium sulfate. To
evaluate the safety of intravenous magnesium sulfate prior to foscarnet infusion by
monitoring blood pressure, heart rate, and heart rhythm. To characterize the effect of
magnesium sulfate on foscarnet blood levels and urinary excretion of calcium, magnesium,
phosphate, and foscarnet.
Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients With Severe Preeclampsia
Completed
University of Utah
N/A
1995-09-01
OBJECTIVES:
I. Determine the effectiveness of nimodipine versus magnesium sulfate in the prevention of
eclamptic seizures in patients with severe preeclampsia.
Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients With Severe Preeclampsia
Completed
FDA Office of Orphan Products Development
N/A
1995-09-01
OBJECTIVES:
I. Determine the effectiveness of nimodipine versus magnesium sulfate in the prevention of
eclamptic seizures in patients with severe preeclampsia.
The purpose of the study is to determine whether magnesium sulfate, given within 8 hours of a
moderate or severe traumatic brain injury improves survival, decreases the number of people
developing seizures, improves the survivors' mental and psychological functioning, including
the ability to return to daily life, live independently, and return to work or school.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.
