Comparison of Acular LS With Lotemax to Prevent Inflammation After Cataract Surgery and Intraocular Lens Implantation
Medical University of South Carolina
The purpose of this study is to compare the effectiveness of Acular LS® and Lotemax® in the
prevention of inflammation in the eye after cataract surgery. Acular LS is made by Allergan,
Inc. It is a nonsteroidal anti-inflammatory drug (NSAID) and is approved by the Food and
Drug Administration (FDA) for use following cataract surgery. Lotemax is made by Bausch &
Lomb. It is a steroid and is also approved by the FDA for use following cataract surgery.
Loteprednol Etabonate Opthalmic Suspension for the Treatment of Dry Eye
Bausch & Lomb Incorporated
This was a single-center, randomized, double-masked, placebo-controlled, parallel-group,
4-visit, CAE (Controlled Adverse Environment) study lasting approximately 4 weeks. Subjects
were randomized to receive loteprednol etabonate ophthalmic suspension, 0.5% or placebo
(vehicle of loteprednol etabonate ophthalmic suspension, 0.5%) and instructed to dose
bilaterally either TID or QID according to randomization.
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