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Last Updated: April 25, 2024

CLINICAL TRIALS PROFILE FOR LOTENSIN HCT


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All Clinical Trials for Lotensin Hct

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00630708 ↗ Safety of Dual Blockage of Rennin-angiotensin System in Patients With Advanced Renal Insufficiency Terminated Nanfang Hospital of Southern Medical University N/A 2008-02-01 The primary aim of the present study is to assess the safety of combined treatment of benazepril (an ACE inhibitor) or losartan (an ARB) in non-diabetic patients with advanced renal insufficiency.
NCT00649038 ↗ Fed Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg Completed Mylan Pharmaceuticals Phase 1 2002-12-01 The objective of this study was to investigate the bioequivalence of Mylan benazepril HCl and hydrochlorothiazide 20 mg/25 mg to Novartis Lotensin HCT® 20 mg/25 mg combination tablets following a single, oral 40 mg/50 mg (2 x 20 mg/25 mg) dose administration under fed conditions.
NCT00649597 ↗ Fasting Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg Completed Mylan Pharmaceuticals Phase 1 2002-11-01 The objective of this study was to investigate the bioequivalence of Mylan benazepril HCl and hydrochlorothiazide 20 mg/25 mg to Novartis Lotensin HCT® 20 mg/25 mg combination tablets following a single, oral 40 mg/50 mg (2 x 20 mg/25 mg) dose administration under fasting conditions.
NCT00836537 ↗ Benazepril HCl 40 mg Tablets, Fed Completed Teva Pharmaceuticals USA Phase 1 2001-03-01 This study will compare the relative bioavailability (rate and extent of absorption) of 40 mg Benazepril Hydrochloride Tablets by TEVA Pharmaceuticals Industries, Ltd. with that of 40 mg LOTENSIN® Tablets by Novartis Pharmaceuticals following a single oral dose (1 x 40 mg) in healthy adult volunteers under non-fasting conditions.
NCT00836576 ↗ Benazepril HCl 40 mg Tablets, Fasting Completed Teva Pharmaceuticals USA Phase 1 2001-02-01 The objective of this randomized, single-dose, two-way crossover evaluation is to compare the oral bioavailability of a test benazepril HCl formulation (TEVA Pharmaceutical Industries Ltd.) to an equivalent oral dose of the commercially available benazepril HCl (Lotensin®, Novartis Pharmaceuticals Corporation) in a test population of 40 adults under fasting conditions.
NCT00907374 ↗ Low Dose Versus Aggressive Inhibition of the Renin-Angiotensin-Aldosterone (RAS) to Treat Microalbuminuria Completed Charles Drew University of Medicine and Science N/A 2005-07-01 The objective of the study is to assess the effect of standard versus aggressive inhibition of the renin-angiotensin system (RAS)in type 2 diabetic patients with microalbuminuria (MA) on; a)progression of microalbuminuria, b)estimated glomerular filtration rate (eGFR), c)endothelial dysfunction (measured by post-hyperemia arterial tonometry) and d)the slowing of the progression of atherosclerotic disease (measured by carotid intima media thickness [CIMT]).
NCT01095939 ↗ Post-preeclampsia Renal Project: Study of Nephroprotection in Women Having Suffered Preeclampsia Completed University Hospital, Geneva Phase 3 2010-04-01 The purpose of the Post-preeclampsia Renal Project is to investigate the renal function of preeclamptic women after delivery, and to determine whether the anti-hypertensive drug named benazepril efficiently improves the dysfunctions observed.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Lotensin Hct

Condition Name

Condition Name for Lotensin Hct
Intervention Trials
Healthy 4
Hypertension 3
Henoch-Schoenlein Purpura Nephritis 2
Renal Insufficiency, Chronic 1
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Condition MeSH

Condition MeSH for Lotensin Hct
Intervention Trials
Purpura, Schoenlein-Henoch 3
Purpura 3
Nephritis 3
Hypertension 2
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Clinical Trial Locations for Lotensin Hct

Trials by Country

Trials by Country for Lotensin Hct
Location Trials
United States 7
China 4
Switzerland 1
Brazil 1
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Trials by US State

Trials by US State for Lotensin Hct
Location Trials
North Dakota 3
Nebraska 1
North Carolina 1
California 1
Missouri 1
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Clinical Trial Progress for Lotensin Hct

Clinical Trial Phase

Clinical Trial Phase for Lotensin Hct
Clinical Trial Phase Trials
Phase 4 2
Phase 3 1
Phase 2 3
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Clinical Trial Status

Clinical Trial Status for Lotensin Hct
Clinical Trial Phase Trials
Completed 8
Recruiting 2
Terminated 2
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Clinical Trial Sponsors for Lotensin Hct

Sponsor Name

Sponsor Name for Lotensin Hct
Sponsor Trials
Nanjing Children's Hospital 2
Mylan Pharmaceuticals 2
Teva Pharmaceuticals USA 2
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Sponsor Type

Sponsor Type for Lotensin Hct
Sponsor Trials
Other 15
Industry 4
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