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Serving hundreds of leading biopharmaceutical companies globally:

Chubb
Teva
US Army
Baxter
US Department of Justice
Farmers Insurance
Daiichi Sankyo
AstraZeneca
McKesson

Generated: December 10, 2018

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CLINICAL TRIALS PROFILE FOR LONSURF

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Clinical Trials for Lonsurf

Trial ID Title Status Sponsor Phase Summary
NCT01896856 Phase I Study of SGI-110 With Irinotecan Followed by Randomized Phase II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Previously Treated Metastatic Colorectal Cancer Recruiting Sidney Kimmel Comprehensive Cancer Center Phase 1/Phase 2 This is a phase I/randomized phase II study of the combination of SGI-110 and previously treated metastatic colorectal cancer patients. This study will be conducted in two components. First, patients will be enrolled in a phase I study of SGI-110 combined with irinotecan in a standard 3+3 design. After the maximum tolerated dose (MTD) is determined, patients will subsequently be enrolled in a 2:1 randomized phase II study of SGI-110 and irinotecan versus the standard of care regorafenib or TAS-102.
NCT02602327 Tas-102 and Radioembolization With 90Y Resin Microspheres for Chemo-refractory Colorectal Liver Metastases Recruiting University of California, San Francisco Phase 1 This is a phase I dose escalation study (3+3 design) with a dose expansion arm (12 patients) designed to evaluate safety of the combination of Tas-102 and radioembolization using Yttrium-90 (90Y) resin microspheres for patients with chemotherapy-refractory liver-dominant chemotherapy-refractory metastatic colorectal cancer (mCRC).
NCT02654639 Ph 2 Study of TAS-102 / Bevacizumab Maintenance Therapy Post Induction Chemotherapy in Metastatic Colorectal Cancer Recruiting Georgetown University Phase 2 Phase II study of TAS-102 plus bevacizumab switch maintenance therapy in patients with mCRC
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Lonsurf

Condition Name

Condition Name for Lonsurf
Intervention Trials
Metastatic Colorectal Cancer 2
Stage IVA Rectal Cancer AJCC v7 2
Stage IVB Rectal Cancer AJCC v7 2
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Condition MeSH

Condition MeSH for Lonsurf
Intervention Trials
Colorectal Neoplasms 7
Rectal Neoplasms 3
Adenocarcinoma 2
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Clinical Trial Locations for Lonsurf

Trials by Country

Trials by Country for Lonsurf
Location Trials
United States 12
Netherlands 1
Japan 1
Germany 1
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Trials by US State

Trials by US State for Lonsurf
Location Trials
California 3
Minnesota 2
Florida 2
Arizona 1
Massachusetts 1
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Clinical Trial Progress for Lonsurf

Clinical Trial Phase

Clinical Trial Phase for Lonsurf
Clinical Trial Phase Trials
Phase 3 1
Phase 2 4
Phase 1/Phase 2 2
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Clinical Trial Status

Clinical Trial Status for Lonsurf
Clinical Trial Phase Trials
Not yet recruiting 8
Recruiting 5
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Clinical Trial Sponsors for Lonsurf

Sponsor Name

Sponsor Name for Lonsurf
Sponsor Trials
Taiho Oncology, Inc. 3
Mayo Clinic 2
National Cancer Institute (NCI) 2
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Sponsor Type

Sponsor Type for Lonsurf
Sponsor Trials
Other 11
Industry 7
NIH 2
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Serving hundreds of leading biopharmaceutical companies globally:

Mallinckrodt
Federal Trade Commission
AstraZeneca
Chinese Patent Office
Covington
Fuji
Queensland Health
Fish and Richardson
Dow

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