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Last Updated: May 26, 2022

CLINICAL TRIALS PROFILE FOR LINZESS


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All Clinical Trials for Linzess

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00730171 ↗ An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation Completed Forest Laboratories Phase 3 2008-09-01 The objective of this study is to assess the long-term safety of linaclotide administered to patients with chronic constipation (CC) or irritable bowel syndrome with constipation (IBS-C).
NCT00730171 ↗ An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation Completed Ironwood Pharmaceuticals, Inc. Phase 3 2008-09-01 The objective of this study is to assess the long-term safety of linaclotide administered to patients with chronic constipation (CC) or irritable bowel syndrome with constipation (IBS-C).
NCT00765999 ↗ An Open-Label, Long-Term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation Completed Ironwood Pharmaceuticals, Inc. Phase 3 2008-10-31 The objective of this study is to assess the long-term safety of linaclotide administered to patients with chronic constipation (CC) or irritable bowel syndrome with constipation (IBS-C).
NCT00765999 ↗ An Open-Label, Long-Term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation Completed Forest Laboratories Phase 3 2008-10-31 The objective of this study is to assess the long-term safety of linaclotide administered to patients with chronic constipation (CC) or irritable bowel syndrome with constipation (IBS-C).
NCT01950403 ↗ Linaclotide Acetate in Preventing Colorectal Cancer in Healthy Volunteers Completed National Cancer Institute (NCI) Phase 1 2013-09-01 This randomized phase I trial studies the side effects and best dose of linaclotide acetate in preventing colorectal cancer in healthy volunteers. Chemoprevention is the use of certain drugs to keep cancer from forming. The use of linaclotide acetate may prevent colorectal cancer.
NCT01950403 ↗ Linaclotide Acetate in Preventing Colorectal Cancer in Healthy Volunteers Completed Mayo Clinic Phase 1 2013-09-01 This randomized phase I trial studies the side effects and best dose of linaclotide acetate in preventing colorectal cancer in healthy volunteers. Chemoprevention is the use of certain drugs to keep cancer from forming. The use of linaclotide acetate may prevent colorectal cancer.
NCT02220348 ↗ A Lactation Study in Women Who Are Breastfeeding or Pumping and Are Receiving Linaclotide Therapeutically Completed Forest Laboratories Phase 1 2014-07-31 The purpose of this study is to determine the amount of linaclotide and its active metabolite (MM-419447) excreted in breast milk after multiple, once daily doses of linaclotide (72 μg, 145 μg, or 290 μg) in lactating women receiving the drug therapeutically.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Linzess

Condition Name

Condition Name for Linzess
Intervention Trials
Irritable Bowel Syndrome With Constipation 5
Chronic Idiopathic Constipation 4
Chronic Constipation 3
Opioid-Induced Constipation 1
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Condition MeSH

Condition MeSH for Linzess
Intervention Trials
Constipation 14
Irritable Bowel Syndrome 8
Syndrome 7
Colorectal Neoplasms 2
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Clinical Trial Locations for Linzess

Trials by Country

Trials by Country for Linzess
Location Trials
United States 274
Canada 8
China 2
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Trials by US State

Trials by US State for Linzess
Location Trials
Pennsylvania 12
Ohio 10
Virginia 10
Texas 10
Louisiana 9
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Clinical Trial Progress for Linzess

Clinical Trial Phase

Clinical Trial Phase for Linzess
Clinical Trial Phase Trials
Phase 4 4
Phase 3 5
Phase 2 5
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Clinical Trial Status

Clinical Trial Status for Linzess
Clinical Trial Phase Trials
Completed 11
Recruiting 3
Terminated 2
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Clinical Trial Sponsors for Linzess

Sponsor Name

Sponsor Name for Linzess
Sponsor Trials
Forest Laboratories 9
Ironwood Pharmaceuticals, Inc. 9
Forest Laboratories, LLC, an Allergan Affiliate 2
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Sponsor Type

Sponsor Type for Linzess
Sponsor Trials
Industry 22
Other 6
NIH 2
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