CLINICAL TRIALS PROFILE FOR LOTREL

All Clinical Trials for LOTREL

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00234871 ↗	Tarka® vs. Lotrel® in Hypertensive, Diabetic Subjects With Renal Disease (TANDEM)	Completed	Abbott	Phase 4	2004-01-01	The primary objective of this study is to determine if trandolapril/verapamil (Tarka®) is superior to amlodipine/benazepril (Lotrel®) in reduction of albuminuria in hypertensive subjects with Type 2 diabetes mellitus (DM) and diabetic nephropathy
NCT00649402 ↗	Fed Study of Amlodipine and Benazepril HCl Capsules 10 mg/20 mg to Lotrel® Capsules 10 mg/20 mg	Completed	Mylan Pharmaceuticals	Phase 1	2004-05-01	The objective of this study was to investigate the bioequivalence of Mylan amlodipine and benazepril HCl 10 mg/20 mg to Novartis Lotrel® 10 mg/20 mg combination capsules following a single, oral 10 mg/20 mg (1 x 10 mg/20 mg) dose administered under fed conditions.
NCT00649519 ↗	Fasting Study of Amlodipine and Benazepril HCl Capsules 10 mg/20 mg to Lotrel® Capsules 10 mg/20 mg	Completed	Mylan Pharmaceuticals	Phase 1	2004-05-01	The objective of this study was to investigate the bioequivalence of Mylan's amlodipine and benazepril HCl 10 mg/20 mg to Novartis' Lotrel® 10 mg/20 mg combination capsules following a single, oral 10 mg/20 mg (1 x 10mg/20mg) dose administered under fasting conditions.
NCT00834977 ↗	Amlodipine-Benazepril 10mg-20mg Capsules in Healthy Subjects Under Fasting Conditions	Completed	Teva Pharmaceuticals USA	Phase 1	2004-04-01	The objective of this study is to compare the rate and extent of absorption of amlodipine-benzazepril 10 mg-20 mg capsules (test) versus Lotrel® (reference), administered as 1 x 10 mg capsule under fasting conditions.
NCT00835367 ↗	Amlodipine-Benazepril 10mg-20mg Capsules in Healthy Subjects Under Fed Conditions	Completed	Teva Pharmaceuticals USA	Phase 1	2004-03-01	The objective of this study is to compare the rate and extent of absorption if amlodipine-benzazepril 10 mg-20 mg capsules (test) versus Lotrel® (reference),administered as 1 x 10 mg- 20 mg capsule under fed conditions.
NCT01155895 ↗	Bioequivalence Study of 10 mg Amlodipine Besylate/ 20 mg Benazepril Hydrochloride Capsules of Dr.Reddys Laboratories Limited Under Fasting Conditions	Completed	Dr. Reddy's Laboratories Limited	Phase 1	2004-03-01	The objective of this study was to compare the single-dose relative bioavailability of Dr. Reddy's Laboratories, Ltd. and Lotrel®) 10 mg amlodipine besylate/20 mg benazepril hydrochloride capsules, under fasting conditions.
NCT01155908 ↗	Bioequivalence Study of 10 mg Amlodipine Besylate/ 20 mg Benazepril Hydrochloride Capsules of Dr.Reddys Laboratories Limited Under Non-fasting (Fed) Conditions	Completed	Dr. Reddy's Laboratories Limited	Phase 1	2005-04-01	The objective of this study was to compare the single-dose relative bioavailability of Dr. Reddy's Laboratories, Ltd. and Lotrel®) 10 mg amlodipine besylate/20 mg benazepril hydrochloride capsules, under non-fasting (fed) conditions.

Clinical Trial Conditions for LOTREL

Condition Name

Condition Name for LOTREL
Intervention	Trials
Healthy	5
Healhty	1
Hypertension	1
Proteinuria	1

Condition MeSH

Condition MeSH for LOTREL
Intervention	Trials
Malnutrition	2
Proteinuria	1
Hypertension	1

Clinical Trial Locations for LOTREL

Trials by Country

Trials by Country for LOTREL
Location	Trials
United States	2
India	2
Canada	2

Trials by US State

Trials by US State for LOTREL
Location	Trials
West Virginia	2

Clinical Trial Progress for LOTREL

Clinical Trial Phase

Clinical Trial Phase for LOTREL
Clinical Trial Phase	Trials
Phase 4	1
Phase 1	8

Clinical Trial Status

Clinical Trial Status for LOTREL
Clinical Trial Phase	Trials
Completed	9

Clinical Trial Sponsors for LOTREL

Sponsor Name

Sponsor Name for LOTREL
Sponsor	Trials
Dr. Reddy's Laboratories Limited	4
Mylan Pharmaceuticals	2
Teva Pharmaceuticals USA	2

Sponsor Type

Sponsor Type for LOTREL
Sponsor	Trials
Industry	9