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Last Updated: March 29, 2024

CLINICAL TRIALS PROFILE FOR KENACORT


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All Clinical Trials for KENACORT

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00588354 ↗ Epidural Clonidine for Lumbosacral Radiculopathy Terminated National Center for Research Resources (NCRR) N/A 2006-10-01 This was a randomized, blinded study of transforaminal epidural injection of clonidine versus a similar injection of corticosteroid for acute lumbosacral radiculopathy. The hypothesis was that clonidine will be as effective as steroid for this condition.
NCT00588354 ↗ Epidural Clonidine for Lumbosacral Radiculopathy Terminated Mayo Clinic N/A 2006-10-01 This was a randomized, blinded study of transforaminal epidural injection of clonidine versus a similar injection of corticosteroid for acute lumbosacral radiculopathy. The hypothesis was that clonidine will be as effective as steroid for this condition.
NCT00999869 ↗ The Comparison Study of Intralesional Botulinum Toxin A and Corticosteroid Injection for Alopecia Areata Unknown status Siriraj Hospital N/A 2009-11-01 Alopecia areata is one of the most common cause of non-scarring alopecia. The pathogenesis is still unclear, however, it is believed to be an autoimmune disease. This disease is not a life-threatening condition but it has a significant psychological impact to patient's quality of life. Many triggers have been proposed such as viral infection, stress and neurologic factors. There are many studies show the correlation between disease activities and neurotransmitters level. Substance P and calcitonin gene-related peptide play major role in early stage of disease. These substances cause imbalance of CD4/CD8 lymphocyte in pathologic site and loss of immune privilege of hair follicles. The conventional treatment of alopecia areata with intralesional corticosteroid injection might treat the end of pathogenesis process. There is no therapeutic intervention for the origin of disease. Fortunately, botulinum toxin A could be a novel treatment of alopecia areata. The botulinum toxin A demonstrates inhibition release of substance P in many publications. To sum up, the treatment of alopecia areata with intralesional corticosteroid injection still be a standard treatment, nevertheless, patients have to receive this treatment every month until regrowth of scalp hair. Corticosteroid injection have several side effects, for example, skin atrophy, pigmentary change and hypothalamic-pituitary-adrenal axis suppression. Moreover, injection pain is also affect to psychological aspect . This study purpose is to evaluate the efficacy of botulinum toxin A for alopecia areata and reduce corticosteroid side effects, as well as, others opportunity cost. There is no prospective, randomized-controlled trial of comparison study between botulinum toxin A injection and corticosteroid injection for alopecia areata, therefore, investigators conduct this study for the greatest benefit to alopecia areata patients and for the future research in disease etiology.
NCT02556424 ↗ Efficacy and Tolerance Comparison Between Subconjunctival Injection of Triamcinolone and Intravitreal Implant of Dexamethasone for the Treatment of Inflammatory Macular Edema Active, not recruiting Nantes University Hospital Phase 3 2016-01-01 Corticosteroids, whether injected peri- or intra-ocularly, remain indispensable tools of the therapeutic arsenal in treating inflammatory macular edema. However, a few years ago, only triamcinolone acetonide was available to ophthalmologists. This molecule, developed initially for rheumatological or dermatological use, has been increasingly deployed in ophthalmology, while still off-label. In 2011, the delivery system of dexamethasone from biodegradable and injectable implant into the vitreous cavity obtained the label for inflammatory macular edema. This protocol is therefore designed to compare the efficacy and safety of peri- and intra-ocular injections of corticosteroids in the treatment of inflammatory macular edema.
NCT02828163 ↗ Comparison Between Injections of Steroids and Autologous Platelet Rich Plasma in the Oral Erosions of Pemphigus Vulgaris Completed Cairo University Phase 3 2016-01-01 Comparing the effect of injecting autologous platelet rich plasma and triamcinolone acetonide in the erosions of buccal mucosa of pemphigus vulgaris patients.
NCT03415165 ↗ Efficacy of Green Tea Buccal Tablets in Oral Lichen Planus Unknown status Cairo University Early Phase 1 2018-01-03 Is topical application of green tea polyphenols buccal tablet more effective in treatment of patients with symptomatic oral lichen planus in comparison with topical application of corticosteroids and what is the most effective concentration of polyphenols
NCT03771768 ↗ Diode Laser Versus Topical Corticosteroids in Management of Oral Ulcers in Behcet's Disease Unknown status Cairo University N/A 2019-05-25 Laser therapy is increasingly showing promising results in dental field including oral ulcers.This trial will assess the usefulness of Diode Laser compared to corticosteroid on oral ulcers of patients diagnosed with Behcet's disease.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for KENACORT

Condition Name

Condition Name for KENACORT
Intervention Trials
Oral Lichen Planus 2
Autoimmune 1
Shoulder Pain 1
Behcet Syndrome 1
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Condition MeSH

Condition MeSH for KENACORT
Intervention Trials
Lichen Planus, Oral 2
Lichen Planus 2
Pemphigus 1
Arthritis, Rheumatoid 1
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Clinical Trial Locations for KENACORT

Trials by Country

Trials by Country for KENACORT
Location Trials
Egypt 5
United States 2
Thailand 2
France 1
Israel 1
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Trials by US State

Trials by US State for KENACORT
Location Trials
New Jersey 1
Minnesota 1
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Clinical Trial Progress for KENACORT

Clinical Trial Phase

Clinical Trial Phase for KENACORT
Clinical Trial Phase Trials
Phase 4 3
Phase 3 2
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for KENACORT
Clinical Trial Phase Trials
Unknown status 4
Completed 4
Recruiting 2
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Clinical Trial Sponsors for KENACORT

Sponsor Name

Sponsor Name for KENACORT
Sponsor Trials
Cairo University 4
Queen Savang Vadhana Memorial Hospital, Thailand 1
National Center for Research Resources (NCRR) 1
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Sponsor Type

Sponsor Type for KENACORT
Sponsor Trials
Other 13
NIH 1
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