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Generated: December 15, 2018

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CLINICAL TRIALS PROFILE FOR JADELLE

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Clinical Trials for Jadelle

Trial ID Title Status Sponsor Phase Summary
NCT01594632 Safety,Effectiveness and Acceptability of Sino-implant II in DR Active, not recruiting Bill and Melinda Gates Foundation N/A A study to assess the contraceptive effectiveness of Sino-implant (II).
NCT01594632 Safety,Effectiveness and Acceptability of Sino-implant II in DR Active, not recruiting FHI 360 N/A A study to assess the contraceptive effectiveness of Sino-implant (II).
NCT02038335 HIV-Target Cell Response in Women Initiating Various Contraceptive Methods in High HIV-Incidence Areas: Zim CHIC Active, not recruiting University of Zimbabwe N/A This study is being done to understand if using birth control causes changes in the immune cells within the reproductive tract of healthy women. Immune cells are important because they help prevent infections from starting and help fight infections that have started. Immune cells are also the type of cells that HIV (human immunodeficiency virus) infects so understanding more about them will help to better understand how to prevent the spread of HIV. Immune cells will be studied from the reproductive tract of women who want to start using one of the following contraceptives: Depo-Provera (DMPA), NET-EN, MPA/E2 (Cyclofem®), the levonorgestrel subdermal implant (Jadelle® ), the etonogestrel subdermal implant (Implanon® or Nexplanon® ) and the copper IUD.
NCT02038335 HIV-Target Cell Response in Women Initiating Various Contraceptive Methods in High HIV-Incidence Areas: Zim CHIC Active, not recruiting University of Pittsburgh N/A This study is being done to understand if using birth control causes changes in the immune cells within the reproductive tract of healthy women. Immune cells are important because they help prevent infections from starting and help fight infections that have started. Immune cells are also the type of cells that HIV (human immunodeficiency virus) infects so understanding more about them will help to better understand how to prevent the spread of HIV. Immune cells will be studied from the reproductive tract of women who want to start using one of the following contraceptives: Depo-Provera (DMPA), NET-EN, MPA/E2 (Cyclofem®), the levonorgestrel subdermal implant (Jadelle® ), the etonogestrel subdermal implant (Implanon® or Nexplanon® ) and the copper IUD.
NCT02103660 Clinical Trial on the Effects of Progestin-based Contraception in the Genital Tract of HIV-infected and Uninfected Women Active, not recruiting Bill and Melinda Gates Foundation Phase 4 The purpose of this study is to determine the acceptability of randomization to contraceptive options and estimate the effect of progestin contraception on HIV genital shedding and inflammatory/immune perturbations in women who may or may not be on antiretroviral therapy, as well as in HIV-uninfected women controls. It is hypothesized that progestin-containing contraception will lead to inflammatory changes that may affect the local immune activity, influencing HIV acquisition or transmissibility risk.
NCT02103660 Clinical Trial on the Effects of Progestin-based Contraception in the Genital Tract of HIV-infected and Uninfected Women Active, not recruiting John E. Fogarty International Center (FIC) Phase 4 The purpose of this study is to determine the acceptability of randomization to contraceptive options and estimate the effect of progestin contraception on HIV genital shedding and inflammatory/immune perturbations in women who may or may not be on antiretroviral therapy, as well as in HIV-uninfected women controls. It is hypothesized that progestin-containing contraception will lead to inflammatory changes that may affect the local immune activity, influencing HIV acquisition or transmissibility risk.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Jadelle

Condition Name

Condition Name for Jadelle
Intervention Trials
Contraception 4
HIV 2
Breastfeeding 1
Post Partum 1
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Condition MeSH

Condition MeSH for Jadelle
Intervention Trials
Uterine Hemorrhage 1
Hemorrhage 1
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Clinical Trial Locations for Jadelle

Trials by Country

Trials by Country for Jadelle
Location Trials
Zimbabwe 1
Uganda 1
Dominican Republic 1
Thailand 1
Malawi 1
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Clinical Trial Progress for Jadelle

Clinical Trial Phase

Clinical Trial Phase for Jadelle
Clinical Trial Phase Trials
Phase 4 2
Phase 2 1
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Jadelle
Clinical Trial Phase Trials
Active, not recruiting 3
Recruiting 2
Not yet recruiting 1
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Clinical Trial Sponsors for Jadelle

Sponsor Name

Sponsor Name for Jadelle
Sponsor Trials
University of Pittsburgh 2
Chulalongkorn University 2
Bill and Melinda Gates Foundation 2
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Sponsor Type

Sponsor Type for Jadelle
Sponsor Trials
Other 11
NIH 2
U.S. Fed 2
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