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Last Updated: December 12, 2024

CLINICAL TRIALS PROFILE FOR IPRATROPIUM BROMIDE


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505(b)(2) Clinical Trials for Ipratropium Bromide

This table shows clinical trials for potential 505(b)(2) applications. See the next table for all clinical trials
Trial Type Trial ID Title Status Sponsor Phase Start Date Summary
OTC NCT00480194 ↗ Evaluation of Safety of ZyComb® In Patients With Common Cold - ZIP 3000 (XY-005-IM) Completed Nycomed 2006-12-01 The objectives of the study are to obtain knowledge about the safety in use, the patients' general impression of the treatment and the pattern of use of ZyComb® in an over-the-counter (OTC) setting.
>Trial Type >Trial ID >Title >Status >Phase >Start Date >Summary

All Clinical Trials for Ipratropium Bromide

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000568 ↗ Lung Health Study (LHS) I and III Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1984-09-01 In the Lung Health Study I, to determine the effects of Special Care, compared to Usual Care, on rate of decline in pulmonary function in a group of cigarette smokers identified as having mild abnormalities in pulmonary function. In the Lung Health Study III, to determine the long-term effects of smoking cessation and continued smoking, on cardiopulmonary morbidity, mortality, and the rate of decline in the one second forced expiratory volume (FEV1) in men and women with early chronic obstructive lung disease who have been followed prospectively for 12 to 15 years.
NCT00000577 ↗ Asthma Clinical Research Network (ACRN) Withdrawn National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1993-09-01 This study will establish a network of interactive asthma clinical research groups to evaluate current therapies, new therapies, and management strategies for adult asthma.
NCT00000577 ↗ Asthma Clinical Research Network (ACRN) Withdrawn Milton S. Hershey Medical Center Phase 3 1993-09-01 This study will establish a network of interactive asthma clinical research groups to evaluate current therapies, new therapies, and management strategies for adult asthma.
NCT00200967 ↗ Asthma Clinical Research Network (ACRN) Trial - Long-Acting Beta Agonist Response by Genotype (LARGE) Completed Asthma Clinical Research Network Phase 3 2004-12-01 The purpose of this trial is to determine whether regularly scheduled use of an inhaled long-acting beta agonist (salmeterol) in the setting of concomitant use of inhaled corticosteroids (beclomethasone hydroflouroalkane (HFA) inhaler) will have a detrimental effect on asthma control in people who bear the B16-Arg/Arg genotype of the beta-2 adrenergic receptor gene, as compared to people with asthma of similar severity who bear the B16-Gly/Gly genotype.
NCT00200967 ↗ Asthma Clinical Research Network (ACRN) Trial - Long-Acting Beta Agonist Response by Genotype (LARGE) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 2004-12-01 The purpose of this trial is to determine whether regularly scheduled use of an inhaled long-acting beta agonist (salmeterol) in the setting of concomitant use of inhaled corticosteroids (beclomethasone hydroflouroalkane (HFA) inhaler) will have a detrimental effect on asthma control in people who bear the B16-Arg/Arg genotype of the beta-2 adrenergic receptor gene, as compared to people with asthma of similar severity who bear the B16-Gly/Gly genotype.
NCT00200967 ↗ Asthma Clinical Research Network (ACRN) Trial - Long-Acting Beta Agonist Response by Genotype (LARGE) Completed Milton S. Hershey Medical Center Phase 3 2004-12-01 The purpose of this trial is to determine whether regularly scheduled use of an inhaled long-acting beta agonist (salmeterol) in the setting of concomitant use of inhaled corticosteroids (beclomethasone hydroflouroalkane (HFA) inhaler) will have a detrimental effect on asthma control in people who bear the B16-Arg/Arg genotype of the beta-2 adrenergic receptor gene, as compared to people with asthma of similar severity who bear the B16-Gly/Gly genotype.
NCT00202176 ↗ Effects of Bronchodilators in Mild Chronic Obstructive Pulmonary Disease (COPD) Completed Queen's University Phase 4 2005-07-01 In people with mild COPD, the ability to exhale air from the lungs is partly limited because of narrowing and collapse of the airways. This results in the trapping of air within the lungs and over-distention of the lungs and chest (lung hyperinflation). Breathing at high lung volumes (hyperinflation) is an important cause of breathing discomfort (dyspnea) in people with COPD. Bronchodilators help to relax muscles in the airways or breathing tubes. Bronchodilators are often prescribed if a cough occurs with airway narrowing as this medication can reduce coughing, wheezing and shortness of breath. Bronchodilators can be taken orally, through injection or through inhalation and begin to act almost immediately but with the effect only lasting 4-6 hours. The main purpose of this study is to examine the effects of inhaled bronchodilators on breathing discomfort and exercise endurance in patients with mild COPD.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Ipratropium Bromide

Condition Name

Condition Name for Ipratropium Bromide
Intervention Trials
Asthma 24
Pulmonary Disease, Chronic Obstructive 16
Chronic Obstructive Pulmonary Disease 11
COPD 7
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Condition MeSH

Condition MeSH for Ipratropium Bromide
Intervention Trials
Pulmonary Disease, Chronic Obstructive 37
Lung Diseases 33
Lung Diseases, Obstructive 27
Asthma 22
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Clinical Trial Locations for Ipratropium Bromide

Trials by Country

Trials by Country for Ipratropium Bromide
Location Trials
United States 114
Canada 11
Germany 7
United Kingdom 6
China 6
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Trials by US State

Trials by US State for Ipratropium Bromide
Location Trials
California 8
North Carolina 7
New York 7
Missouri 6
Colorado 5
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Clinical Trial Progress for Ipratropium Bromide

Clinical Trial Phase

Clinical Trial Phase for Ipratropium Bromide
Clinical Trial Phase Trials
Phase 4 28
Phase 3 23
Phase 2/Phase 3 1
[disabled in preview] 30
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Clinical Trial Status

Clinical Trial Status for Ipratropium Bromide
Clinical Trial Phase Trials
Completed 60
Unknown status 6
Terminated 6
[disabled in preview] 13
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Clinical Trial Sponsors for Ipratropium Bromide

Sponsor Name

Sponsor Name for Ipratropium Bromide
Sponsor Trials
Boehringer Ingelheim 23
GlaxoSmithKline 5
Laval University 4
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Sponsor Type

Sponsor Type for Ipratropium Bromide
Sponsor Trials
Other 77
Industry 45
NIH 4
[disabled in preview] 1
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