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Generated: June 26, 2019

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CLINICAL TRIALS PROFILE FOR IOTHALAMATE SODIUM I-125

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Clinical Trials for Iothalamate Sodium I-125

Trial ID Title Status Sponsor Phase Summary
NCT00270829 Renal Effects of Intrarenal Nesiritide Terminated University of Maryland Phase 4 The impact of nesiritide in CHF is unclear, but it is possible that systemic vasodilation leads to adverse consequences even if the direct renal effects are positive. Therefore, this study will look at the effects of direct intrarenal administration of nesiritide on GFR and RPF.
NCT01836809 Nesiritide and Renal Function After the Total Artificial Heart Terminated Virginia Commonwealth University Phase 4 The prevalence of renal dysfunction after implantation of the artificial heart is high. The infusion of exogenous B-type natriuretic peptide (BNP) after implantation of the total artificial heart (TAH) improves renal function in a sustained manner. The renal protective and hormone-modulating effects of nesiritide may be enhanced with ventriculectomy compared to heart failure surgery that leaves the native myocardium intact. The goal of this project is to determine the renal protective effects of nesiritide after implantation of a mechanical device.
NCT01970176 Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim2) Recruiting Mayo Clinic Phase 1/Phase 2 To determine the effect of 12 weeks of chronic PDEV inhibition with Tadalafil versus placebo on basal cardiorenal and humoral function and on the integrated cardiorenal and humoral response to acute sodium loading in subjects with preclinical systolic dysfunction (PSD) and renal (kidney) dysfunction.
NCT02058095 Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim3) Recruiting Mayo Clinic Phase 1/Phase 2 To determine the effect of 12 weeks of chronic PDEV inhibition with Tadalafil versus placebo on basal cardiorenal and humoral function and on the integrated cardiorenal and humoral response to acute sodium loading in subjects with preclinical Diastolic dysfunction (PDD) and renal (kidney) dysfunction
NCT03019653 Safety and Efficacy of ANX-042 in Human Cardiorenal Syndrome Enrolling by invitation National Heart, Lung, and Blood Institute (NHLBI) Phase 1 The purpose of this study is to look at kidney function and hormonal function in patients with a history of heart failure and kidney dysfunction, and to see how the use of a new drug, ANX-042, affects those functions.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Iothalamate Sodium I-125

Condition Name

Condition Name for Iothalamate Sodium I-125
Intervention Trials
Renal Impairment 2
Cardiomyopathy 2
Congestive Heart Failure 1
Cardiorenal Syndrome 1
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Condition MeSH

Condition MeSH for Iothalamate Sodium I-125
Intervention Trials
Heart Failure 3
Renal Insufficiency 3
Cardiomyopathies 2
Cardio-Renal Syndrome 2
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Clinical Trial Locations for Iothalamate Sodium I-125

Trials by Country

Trials by Country for Iothalamate Sodium I-125
Location Trials
United States 6
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Trials by US State

Trials by US State for Iothalamate Sodium I-125
Location Trials
Minnesota 4
Virginia 1
Maryland 1
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Clinical Trial Progress for Iothalamate Sodium I-125

Clinical Trial Phase

Clinical Trial Phase for Iothalamate Sodium I-125
Clinical Trial Phase Trials
Phase 4 2
Phase 2 1
Phase 1/Phase 2 2
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Clinical Trial Status

Clinical Trial Status for Iothalamate Sodium I-125
Clinical Trial Phase Trials
Recruiting 3
Terminated 2
Enrolling by invitation 1
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Clinical Trial Sponsors for Iothalamate Sodium I-125

Sponsor Name

Sponsor Name for Iothalamate Sodium I-125
Sponsor Trials
Mayo Clinic 4
Virginia Commonwealth University 1
University of Maryland 1
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Sponsor Type

Sponsor Type for Iothalamate Sodium I-125
Sponsor Trials
Other 6
NIH 2
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