Comparison of the Ability of Glulisine With Lispro to Control Type 1 Diabetes Mellitus in Children and Adolescents
The purpose of this study is to determine if insulin glulisine (Apidra) is as safe and
effective a rapid acting insulin as insulin lispro (Humalog) in children and adolescents
with type 1 diabetes mellitus.
Insulin Glulisine in Adult Subjects With Type 2 Diabetes Receiving Insulin Glargine as Basal Insulin
The purpose of this study is to compare the change in glycemic control, as measured by
hemoglobin A1c (HbA1c) from baseline to study week 24, in subjects receiving insulin
glulisine as mealtime insulin following a variable bolus insulin regimen (based on
carbohydrate counting) versus a fixed bolus insulin regimen, with insulin glargine as basal
insulin in both arms of the study.
Variable Bolus Regimen 1-2-3 for Type 2 Diabetes Mellitus
The purpose of this study is to show the non-inferiority of insulin glulisine administered
with 1 meal versus 2 meals versus 3 daily meals, as measured by the change in hemoglobin A1c
(HbA1c), from baseline to study week 24.
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