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Last Updated: May 26, 2022

CLINICAL TRIALS PROFILE FOR INDOMETHACIN


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All Clinical Trials for Indomethacin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000494 ↗ Management of Patent Ductus in Premature Infants Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1978-09-01 To evaluate the effects (up to one year of age) of indomethacin on the clinical course of patent ductus arteriosus (PDA) in premature infants (24 hours old or less) and to assess the relative merits of indomethacin and surgery in infants with persistent respiratory distress who were not treated early with indomethacin. Two concurrent trials were performed.
NCT00002535 ↗ Indomethacin Plus Biological Therapy in Treating Patients With Advanced Melanoma Completed St. Luke's Medical Center Phase 2 1993-07-01 RATIONALE: Biological therapies use different ways to stimulate the immune system and stop tumor cells from growing. Combining biological therapies with indomethacin and cyclophosphamide may kill more tumor cells. PURPOSE: Phase II trial to compare the effectiveness of indomethacin and biological therapy with or without cyclophosphamide in treating patients who have advanced melanoma that has not responded to previous therapy.
NCT00002796 ↗ Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer Terminated National Cancer Institute (NCI) Phase 1/Phase 2 1997-05-01 Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Interferon-gamma may interfere with the growth of tumor cells and slow the growth of the tumor. Combining more than one drug with interferon-gamma may kill more tumor cells. This phase I/II trial is studying the side effects and best dose of giving fluorouracil together with phenylbutyrate, indomethacin, and interferon-gamma and to see how well it works in treating patients with stage IV colorectal cancer
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Indomethacin

Condition Name

Condition Name for Indomethacin
Intervention Trials
Patent Ductus Arteriosus 14
Post-ERCP Acute Pancreatitis 8
Healthy 6
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Condition MeSH

Condition MeSH for Indomethacin
Intervention Trials
Pancreatitis 26
Ductus Arteriosus, Patent 24
Premature Birth 16
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Clinical Trial Locations for Indomethacin

Trials by Country

Trials by Country for Indomethacin
Location Trials
United States 277
Canada 32
China 25
India 18
Taiwan 9
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Trials by US State

Trials by US State for Indomethacin
Location Trials
California 17
Texas 16
Michigan 14
Ohio 13
New York 12
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Clinical Trial Progress for Indomethacin

Clinical Trial Phase

Clinical Trial Phase for Indomethacin
Clinical Trial Phase Trials
Phase 4 38
Phase 3 33
Phase 2/Phase 3 10
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Clinical Trial Status

Clinical Trial Status for Indomethacin
Clinical Trial Phase Trials
Completed 95
Unknown status 25
Recruiting 14
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Clinical Trial Sponsors for Indomethacin

Sponsor Name

Sponsor Name for Indomethacin
Sponsor Trials
Chelsea Therapeutics 4
Iroko Pharmaceuticals, LLC 4
National Cancer Institute (NCI) 4
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Sponsor Type

Sponsor Type for Indomethacin
Sponsor Trials
Other 205
Industry 47
NIH 16
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