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Generated: December 18, 2018

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CLINICAL TRIALS PROFILE FOR IMPAVIDO

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Clinical Trials for Impavido

Trial ID Title Status Sponsor Phase Summary
NCT01122771 Phase III, Study of Three Short Course Combo (Ambisome®, Miltefosine, Paromomycin) Compared With AmBisome for the Treatment of VL in Bangladesh Completed International Centre for Diarrhoeal Disease Research, Bangladesh Phase 3 This protocol will evaluate the efficacy and safety of various combinations of the three drugs; AmBisome, Paromomycin and Miltefosine at reduced total dosage against the standard treatment with a total dose of 15mg/kg of AmBisome.
NCT01122771 Phase III, Study of Three Short Course Combo (Ambisome®, Miltefosine, Paromomycin) Compared With AmBisome for the Treatment of VL in Bangladesh Completed Shaheed Surhawardy Medical College and Hospital Phase 3 This protocol will evaluate the efficacy and safety of various combinations of the three drugs; AmBisome, Paromomycin and Miltefosine at reduced total dosage against the standard treatment with a total dose of 15mg/kg of AmBisome.
NCT01122771 Phase III, Study of Three Short Course Combo (Ambisome®, Miltefosine, Paromomycin) Compared With AmBisome for the Treatment of VL in Bangladesh Completed Drugs for Neglected Diseases Phase 3 This protocol will evaluate the efficacy and safety of various combinations of the three drugs; AmBisome, Paromomycin and Miltefosine at reduced total dosage against the standard treatment with a total dose of 15mg/kg of AmBisome.
NCT01377974 Clinical Trial of Miltefosine to Treat Mucosal Leishmaniasis Completed Brasilia University Hospital Phase 2 The purpose of this study is to determine whether miltefosine is effective in the treatment of mucosal leishmaniasis compared to meglumine antimoniate, the standard treatment.
NCT02011958 Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients. Active, not recruiting Addis Ababa University Phase 3 The overall objective of this trial is to identify a safe and effective treatment for visceral leishmaniasis (VL) in HIV co-infected Ethiopian patients. Patients will receive either Ambisome alone or Ambisome in combination with Miltefosine. Patients who do not undergo treatment failure will be given a VL prophylactic treatment with Pentamidine one month after the end of the study treatment.
NCT02011958 Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients. Active, not recruiting Institute of Tropical Medicine, Belgium Phase 3 The overall objective of this trial is to identify a safe and effective treatment for visceral leishmaniasis (VL) in HIV co-infected Ethiopian patients. Patients will receive either Ambisome alone or Ambisome in combination with Miltefosine. Patients who do not undergo treatment failure will be given a VL prophylactic treatment with Pentamidine one month after the end of the study treatment.
NCT02011958 Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients. Active, not recruiting London School of Hygiene and Tropical Medicine Phase 3 The overall objective of this trial is to identify a safe and effective treatment for visceral leishmaniasis (VL) in HIV co-infected Ethiopian patients. Patients will receive either Ambisome alone or Ambisome in combination with Miltefosine. Patients who do not undergo treatment failure will be given a VL prophylactic treatment with Pentamidine one month after the end of the study treatment.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Impavido

Condition Name

Condition Name for Impavido
Intervention Trials
Visceral Leishmaniasis 3
Leishmaniasis 2
Mucocutaneous Leishmaniasis 2
Cutaneous Leishmaniasis 1
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Condition MeSH

Condition MeSH for Impavido
Intervention Trials
Leishmaniasis 10
Leishmaniasis, Visceral 4
Leishmaniasis, Mucocutaneous 3
Leishmaniasis, Cutaneous 1
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Clinical Trial Locations for Impavido

Trials by Country

Trials by Country for Impavido
Location Trials
Sudan 2
Ethiopia 2
Kenya 2
Bangladesh 1
Brazil 1
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Clinical Trial Progress for Impavido

Clinical Trial Phase

Clinical Trial Phase for Impavido
Clinical Trial Phase Trials
Phase 3 3
Phase 2 3
N/A 4
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Clinical Trial Status

Clinical Trial Status for Impavido
Clinical Trial Phase Trials
Not yet recruiting 6
Completed 2
Active, not recruiting 1
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Clinical Trial Sponsors for Impavido

Sponsor Name

Sponsor Name for Impavido
Sponsor Trials
Drugs for Neglected Diseases 5
Knight Therapeutics (USA) Inc 4
University of Gondar 2
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Sponsor Type

Sponsor Type for Impavido
Sponsor Trials
Other 19
Industry 4
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