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Last Updated: November 14, 2019

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CLINICAL TRIALS PROFILE FOR ICODEXTRIN

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All Clinical Trials for Icodextrin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00004987 Treatment of Advanced AIDS Patients With Dextrin Sulfate Unknown status Steinhart Medical Associates Phase 1 1999-10-01 The purpose of this study is to look at the safety and effectiveness of dextrin sulfate in AIDS patients who have failed conventional anti-HIV treatment.
NCT00119990 Changes in Cardiovascular Hemodynamics During Peritoneal Dialysis Terminated University of Aarhus N/A 2006-01-01 During peritoneal dialysis, water is removed from the body. This sometimes occurs at rates of up to 500 ml/h. During shifts with dialysate with high glucose content, an increase in blood pressure has been described. The effect upon central hemodynamics is unknown. The researchers are investigating the effects of low and high glucose dialysate and icodextrin on cardiac output, stroke volume, pulse rate and blood pressure. The researchers have hypothesized that the effects seen are induced by vasopressin.
NCT00369096 Efficacy Study of the Addition of Bemiparin to Icodextrin Solution in Peritoneal Dialysis Patients (Bemidextrina) Completed Infociencia S.L Phase 2 2006-09-01 The purpose of this study is to evaluate whether addition of bemiparin, once daily in icodextrin solution for peritoneal dialysis for 16 weeks, increases the peritoneal capacity for ultrafiltration and/or reduces creatinine transport in peritoneal dialysis patients presenting functional disorders related to ultrafiltration deficit and/or high transport.
NCT00369096 Efficacy Study of the Addition of Bemiparin to Icodextrin Solution in Peritoneal Dialysis Patients (Bemidextrina) Completed Fundación Renal Iñigo Alvarez De Toledo Phase 2 2006-09-01 The purpose of this study is to evaluate whether addition of bemiparin, once daily in icodextrin solution for peritoneal dialysis for 16 weeks, increases the peritoneal capacity for ultrafiltration and/or reduces creatinine transport in peritoneal dialysis patients presenting functional disorders related to ultrafiltration deficit and/or high transport.
NCT00397358 Effect of Extraneal (Icodextrin)on Triglyceride Levels in PD Patients Terminated Baxter Healthcare Corporation Phase 4 2006-11-01 This is a Phase IV study evaluating triglyceride levels in peritoneal dialysis patients.
NCT00725517 Efficacy and Safety of a 7.5% Icodextrin Peritoneal Dialysis Solution in Once-Daily Long Dwell Exchange Completed Shanghai Jiao Tong University School of Medicine Phase 4 2005-12-01 The purpose of this study is to evaluate the efficacy and safety of a 7.5% Icodextrin peritoneal dialysis solution for once-daily long dwell exchange in patients undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD) in Chinese uremic patients.Patients were divided into Dianeal group or Extraneal group for long dwell time. Net ultrafiltration, small solute clearance and relationship between different transport group were used to evaluate efficacy of Icodextrin. Physical examination, vital signs and laboratory tests were used to evaluate safety of Icodextrin.
NCT01044446 Effect of Icodextrin on the Treatment Outcome of Peritoneal Dialysis Patients During Acute Peritonitis Completed Chinese University of Hong Kong Phase 4 2010-01-01 The objective of the present study is to evaluate the a prior hypothesis that treatment with icodextrin during acute peritonitis would improve the treatment outcomes of peritonitis complicating peritoneal dialysis. The safety and effectiveness of icodextrin for decreasing glucose exposure, extent and severity of peritonitis will be evaluated in the setting of acute peritonitis complicating peritoneal dialysis among patients who are not receiving icodextrin.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Icodextrin

Condition Name

Condition Name for Icodextrin
Intervention Trials
End Stage Renal Disease 4
Peritoneal Dialysis 3
Hypertriglyceridemia 1
Surgical Adhesions 1
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Condition MeSH

Condition MeSH for Icodextrin
Intervention Trials
Kidney Failure, Chronic 5
Peritonitis 2
Tissue Adhesions 1
Kidney Diseases 1
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Clinical Trial Locations for Icodextrin

Trials by Country

Trials by Country for Icodextrin
Location Trials
United States 5
Spain 5
Korea, Republic of 2
Sweden 1
Denmark 1
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Trials by US State

Trials by US State for Icodextrin
Location Trials
Pennsylvania 1
Nebraska 1
Indiana 1
California 1
Florida 1
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Clinical Trial Progress for Icodextrin

Clinical Trial Phase

Clinical Trial Phase for Icodextrin
Clinical Trial Phase Trials
Phase 4 4
Phase 3 2
Phase 2 3
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Clinical Trial Status

Clinical Trial Status for Icodextrin
Clinical Trial Phase Trials
Recruiting 4
Completed 4
Unknown status 3
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Clinical Trial Sponsors for Icodextrin

Sponsor Name

Sponsor Name for Icodextrin
Sponsor Trials
Baxter Healthcare Corporation 4
Iperboreal Pharma Srl 2
Lawson Health Research Institute 1
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Sponsor Type

Sponsor Type for Icodextrin
Sponsor Trials
Other 13
Industry 7
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