A Randomized, Double-blind, Parallel-group Assessment of the Safety and Efficacy of Telmisartan 40mg Plus Hydrochlorothiazide 12.5mg (Micardis Plus) in Comparison With Losartan 50mg Plus Hydrochlorothiazide 12.5mg in Taiwanese Patients With Mild to
The primary objective of this trial is to compare the efficacy and safety of telmisartan 40
mg/hydrochlorothiazide 12.5mg (Micardis Plus) with that of losartan 50 mg/hydrochlorothiazide
12.5 mg, a reference AIIA combined with diuretic, in Taiwanese patients with mild to moderate
Combination of Telmisartan 40 mg Plus Hydrochlorothiazide (HCTZ) 12.5 mg vs. Telmisartan 40 mg Alone in Patients With Essential Hypertension Who Fail to Respond Adequately to Telmisartan Monotherapy
The objective of this trial is to demonstrate that the fixed dose combination of telmisartan
40 mg and HCTZ 12.5 mg is superior to the monocomponent of telmisartan (Micardis, Gliosartan,
Kinzal, Kinzalmono, Predxal, Pritor, Samertan, Telmisartan) 40 mg in patients with essential
hypertension who fail to respond adequately to telmisartan monotherapy.
Combination of Telmisartan 80 mg Plus Hydrochlorothiazide 12.5 mg to Telmisartan 80 mg in Patients Failed in Telmisartan 80 mg
To demonstrate that a fixed dose combination of telmisartan 80 mg plus HCTZ 12.5 mg is
superior to telmisartan 80 mg alone in patients, who fail to respond adequately to
telmisartan 80 mg monotherapy, in lowering seated trough diastolic blood pressure after eight
weeks of treatment.
3 x 3 Factorial Trial of Telmisartan and Hydrochlorothiazide in Patients With Essential Hypertension
1. To investigate the dose response of the combination therapy, Telmisartan and
Hydrochlorothiazide for the Japanese patients with Essential Hypertension.
2. To compare this dose response with that in the US study.
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