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Generated: June 26, 2019

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CLINICAL TRIALS PROFILE FOR HYDROCHLOROTHIAZIDE; QUINAPRIL HYDROCHLORIDE

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Clinical Trials for Hydrochlorothiazide; Quinapril Hydrochloride

Trial ID Title Status Sponsor Phase Summary
NCT00515021 Diurnal Variation of Plasminogen Activator Inhibitor-1 Unknown status National Center for Research Resources (NCRR) Phase 4 To determine if nighttime administration of an aldosterone antagonist would effectively lower peak plasma PAI-1 levels more effectively than morning administration.
NCT00515021 Diurnal Variation of Plasminogen Activator Inhibitor-1 Unknown status Vanderbilt University Medical Center Phase 4 To determine if nighttime administration of an aldosterone antagonist would effectively lower peak plasma PAI-1 levels more effectively than morning administration.
NCT00648011 Food Study of Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Accuretic™ Tablets 20 mg/25 mg Completed Mylan Pharmaceuticals Phase 1 The objective of this study was to investigate the bioequivalence of Mylan's quinapril HCl and hydrochlorothiazide 20 mg/25 mg tablets to Parke-Davis' Accuretic™ 20mg/ 25 mg tablets following a single, oral 20/25 mg (1 x 20/25 mg) dose administration under fed conditions.
NCT00649441 Fasting Study of Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Accuretic™ Tablets 20 mg/25 mg Completed Mylan Pharmaceuticals Phase 1 The objective of this study was to investigate the bioequivalence of Mylan's quinapril HCl and hydrochlorothiazide 20 mg/25 mg tablets to Parke-Davis' Accuretic™ 20 mg/25 mg tablets following a single, oral 20 mg/25 mg (1 x 20 mg/25 mg) dose administered under fasting conditions.
NCT00651287 A Study to Evaluate the Efficacy and Safety of Quinapril or Quinapril Plus Hydrochlorothiazide in Patients With Mild to Moderate Hypertension Completed Pfizer Phase 4 The purpose of this study is to determine the response rate for the therapeutic goal (diastolic blood pressure (BP) less than 90 mmHg and systolic BP less than 140 mmHg) at Week 6 for quinapril 20 mg and at Week 12 for quinapril 20 mg, quinapril 40 mg, and quinapril 20 mg plus hydrochlorothiazide 12.5 mg; and to determine the mean decrease in diastolic and systolic BP measurements and the change in heart rate at Week 6 and Week 12 compared with baseline.
NCT00872235 Bioequivalence Study of Quinapril Hydrochloride 20 mg and Hydrochlorothiazide 25 mg Tablets Under Fed Conditions Completed Ranbaxy Laboratories Limited N/A This open-label, balanced, randomized, two-treatment, four-period, two-sequence, single dose, crossover fully replicated study was conducted on fixed-dose combination of quinapril 20 mg and hydrochlorothiazide 25 mg tablets of OHM Laboratories Inc. (division of Ranbaxy Laboratories Limited) and Accuretic 20-25 mg tablets of Parke-Davis (division of Pfizer Inc.) in healthy, adult, human, male, subjects under fed conditions.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Hydrochlorothiazide; Quinapril Hydrochloride

Condition Name

Condition Name for Hydrochlorothiazide; Quinapril Hydrochloride
Intervention Trials
Healthy 4
Hypertension 2
Type 2 Diabetes Mellitus 1
Metabolic Syndrome X 1
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Condition MeSH

Condition MeSH for Hydrochlorothiazide; Quinapril Hydrochloride
Intervention Trials
Hypertension 2
Diabetes Mellitus, Type 2 1
Diabetes Mellitus 1
Metabolic Syndrome X 1
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Clinical Trial Locations for Hydrochlorothiazide; Quinapril Hydrochloride

Trials by Country

Trials by Country for Hydrochlorothiazide; Quinapril Hydrochloride
Location Trials
United States 3
Turkey 2
India 2
Romania 1
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Trials by US State

Trials by US State for Hydrochlorothiazide; Quinapril Hydrochloride
Location Trials
North Dakota 2
Tennessee 1
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Clinical Trial Progress for Hydrochlorothiazide; Quinapril Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Hydrochlorothiazide; Quinapril Hydrochloride
Clinical Trial Phase Trials
Phase 4 3
Phase 1 2
N/A 2
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Clinical Trial Status

Clinical Trial Status for Hydrochlorothiazide; Quinapril Hydrochloride
Clinical Trial Phase Trials
Completed 6
Unknown status 1
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Clinical Trial Sponsors for Hydrochlorothiazide; Quinapril Hydrochloride

Sponsor Name

Sponsor Name for Hydrochlorothiazide; Quinapril Hydrochloride
Sponsor Trials
Mylan Pharmaceuticals 2
Ranbaxy Laboratories Limited 2
Pfizer 1
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Sponsor Type

Sponsor Type for Hydrochlorothiazide; Quinapril Hydrochloride
Sponsor Trials
Industry 6
Other 1
NIH 1
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