Comparison of a Twice Daily Versus a Three Times Daily Insulin Regimen in Children With Type 1 Diabetes
Completed
University of Calgary
N/A
2008-03-01
The purpose of this study is to determine whether there is a difference in blood sugar
control (as measured by hemoglobin A1c (HA1c)), in children given twice daily insulin
injections incorporating a new long acting insulin analogue (detemir) compared to children
using their current three times a day insulin injections (with intermediate and rapid acting
insulin).
Evaluating Pharmacokinetics and Pharmacodynamics of Jusline
Completed
King Saud University
N/A
2006-11-01
To evaluate the pharmacokinetic and pharmacodynamic profile of a new human insulin (Jusline)
after subcutaneous administration, and to compare this profile with Humulin insulin.
Effect of Single Dose Intranasal Insulin On Cognitive Function
Completed
University of Massachusetts, Worcester
Phase 4
2006-10-01
The purpose of the study is to find out how a small dose of insulin might affect memory, the
ability to concentrate, and improve your daily functioning in patients with schizophrenia and
schizoaffective disorders. Insulin is not being used to treat diabetes in this study. The
investigators propose a single dose, double-blinded, placebo-controlled trial of intranasal
insulin in 40 subjects with schizophrenia or schizoaffective disorder to examine insulin's
effect on cognition. The specific aims include:
1. Examine the effects of single doses of 40 IU intranasal insulin compared to placebo on
cognitive functioning, including attention and memory.
2. Examine whether single dose of intranasal insulin administration will raise serum
insulin level and decrease plasma glucose level
Insulin will be delivered through an air spray pump into your nose. The investigators will be
comparing one dose of insulin (40 International Units) with placebo, an inactive liquid.
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