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Last Updated: April 21, 2024

CLINICAL TRIALS PROFILE FOR HEMADY


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All Clinical Trials for Hemady

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00098475 ↗ Lenalidomide and Dexamethasone With or Without Thalidomide in Treating Patients With Multiple Myeloma Active, not recruiting National Cancer Institute (NCI) Phase 3 2004-10-26 This randomized phase III trial studies lenalidomide and low-dose dexamethasone to see how well it works compared to lenalidomide and standard-dose dexamethasone, given with or without thalidomide, in treating patients with multiple myeloma. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Lenalidomide and thalidomide may also stop the growth of multiple myeloma by blocking blood flow to the cancer. Drugs used in chemotherapy, such as dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving lenalidomide, thalidomide, and dexamethasone together may kill more cancer cells.
NCT00408005 ↗ Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Active, not recruiting National Cancer Institute (NCI) Phase 3 2007-01-22 This randomized phase III trial is studying different combination chemotherapy regimens and their side effects and comparing how well they work in treating young patients with newly diagnosed T-cell acute lymphoblastic leukemia or T-cell lymphoblastic lymphoma. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating T-cell acute lymphoblastic leukemia or T-cell lymphoblastic lymphoma. After a common induction therapy, patients were risk assigned and eligible for one or both post-induction randomizations: Escalating dose Methotrexate versus High Dose Methotrexate in Interim Maintenance therapy, No Nelarabine versus Nelarabine in Consolidation therapy. T-ALL patients are risk assigned as Low Risk, Intermediate Risk or High Risk. Low Risk patients are not eligible for the Nelarabine randomization, Patients with CNS disease at diagnosis were assgined to receive High Dose Methotrexate, patients who failed induction therapy were assigned to receive Nelarabine and High Dose Methotrexate. T-LLy patients were all assigned to escalating dose Methotrexate and were risk assigned as Standard Risk, High Risk and induction failures. Standard risk patients did not receive nelarabine, High risk T-LLy patients were randomized to No Nelarabine versus Nelarabine, and Induction failures were assigned to receive Nelarabine.
NCT00644228 ↗ Lenalidomide and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Multiple Myeloma Active, not recruiting National Cancer Institute (NCI) Phase 3 2008-04-01 This randomized phase III trial studies lenalidomide, dexamethasone, and bortezomib to see how well it works compared to dexamethasone and lenalidomide alone in treating patients with previously untreated multiple myeloma. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Drugs used in chemotherapy, such as dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth or by blocking blood flow to the cancer. It is not yet known whether lenalidomide and dexamethasone is more effective with or without bortezomib in treating multiple myeloma.
NCT00792948 ↗ Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia Active, not recruiting National Cancer Institute (NCI) Phase 2 2009-09-01 This phase II trial is studying the side effects of giving combination chemotherapy together with or without donor stem cell transplant and to see how well it works in treating patients with acute lymphoblastic leukemia. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. Giving chemotherapy and total-body irradiation before a donor stem cell transplant helps stop the growth of cancer cells. It also stops the patient's immune system from rejecting the donor's stem cells. The donated stem cells may replace the patient's immune cells and help destroy any remaining cancer cells (graft-versus-tumor effect).
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Hemady

Condition Name

Condition Name for Hemady
Intervention Trials
Recurrent Plasma Cell Myeloma 10
Refractory Plasma Cell Myeloma 10
Plasma Cell Myeloma 6
Untreated Adult Acute Lymphoblastic Leukemia 5
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Condition MeSH

Condition MeSH for Hemady
Intervention Trials
Neoplasms, Plasma Cell 16
Multiple Myeloma 16
Leukemia 12
Precursor Cell Lymphoblastic Leukemia-Lymphoma 12
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Clinical Trial Locations for Hemady

Trials by Country

Trials by Country for Hemady
Location Trials
United States 614
Canada 51
Australia 23
New Zealand 10
Puerto Rico 8
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Trials by US State

Trials by US State for Hemady
Location Trials
Minnesota 22
California 20
Georgia 17
Florida 17
Ohio 17
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Clinical Trial Progress for Hemady

Clinical Trial Phase

Clinical Trial Phase for Hemady
Clinical Trial Phase Trials
Phase 3 10
Phase 2/Phase 3 1
Phase 2 13
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Clinical Trial Status

Clinical Trial Status for Hemady
Clinical Trial Phase Trials
Recruiting 15
Not yet recruiting 13
Active, not recruiting 10
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Clinical Trial Sponsors for Hemady

Sponsor Name

Sponsor Name for Hemady
Sponsor Trials
National Cancer Institute (NCI) 35
Mayo Clinic 8
Emory University 2
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Sponsor Type

Sponsor Type for Hemady
Sponsor Trials
NIH 35
Other 22
Industry 3
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