Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by Opioids
Completed
Stanford University
Phase 2
2009-02-01
This research study explores whether a beta-blocker (propranolol) can prevent a person from
becoming more sensitive to pain after administration of an opioid (remifentanil). Beta
blockers inhibit the sympathetic (fight or flight) response and are often used to treat
angina and high blood pressure. In a previous study in human volunteers, the investigators
demonstrated an increased sensitivity to pain after a 60-minute infusion of the opioid
remifentanil. The goal of this study is to identify a possible inhibitor of this phenomenon.
Propranolol Dose Escalation in Lymphedema in Patients
Terminated
Columbia University
Phase 2
2017-06-07
This is a study to investigate the safety and efficacy of propranolol in the treatment of
patients with primary lymphedema. The primary goal is to assess patient tolerability of
increasing doses of propranolol. The secondary goal is to assess lymphedema symptoms and
signs in response to propranolol treatment.
Trial of Propranolol in Children and Youth With Autism Spectrum Disorder and Predictors of Response
Completed
United States Department of Defense
Early Phase 1
2016-08-01
The purpose of this study is to find out how the brain of people with autism is affected by
Propranolol. Propranolol is not FDA approved for the treatment of autism. Propranolol is FDA
approved for the treatment of heart conditions such as blood pressure
This research is being done because there are currently no drug treatment options for
language impairments and social difficulties often experienced by people with autism.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.
