Study on the Prognosis and Effect of Anti-diabetic Drugs on Type-2 Diabetes Mellitus With Coronary Artery Disease
Completed
Shanghai Jiao Tong University School of Medicine
Phase 4
2004-06-01
The purpose of this study is to explore the recurrence risk of cardiovascular events in
patients with type 2 diabetes mellitus and coronary heart disease after different
antidiabetic drug therapy (glipizide or metformin) by using an double-blind, randomized,
parallel control and prospective study
The end point of this study is:
1. follow up 3yr
2. recurrence of cardiovascular event
3. death caused by other reasons such as stroke, uremia, blindness and amputation
Food Study of Glipizide and Metformin HCl Tablets 5 mg/500 mg to Metaglip® Tablets 5 mg/500 mg
Completed
Mylan Pharmaceuticals
Phase 1
2005-06-01
The objective of this study was to investigate the bioequivalence of Mylan's glipizide and
metformin HCl 5 mg/500 mg tablets to Bristol-Myers Squibb's Metaglip® 5 mg/500 mg tablets
following a single, oral 5 mg/500 mg (1 x 5 mg/500 mg) dose administration under fed
conditions.
Fasting Study of Glipizide and Metformin HCl Tablets 5 mg/500 mg to Metaglip® Tablets 5 mg/500 mg
Completed
Mylan Pharmaceuticals
Phase 1
2005-06-01
The objective of this study was to investigate the bioequivalence of Mylan's glipizide and
metformin HCl 5 mg/500 mg tablets to Bristol-Myers Squibb's Metaglip® 5 mg/500 mg tablets
following a single, oral 5 mg/500 mg (1 x 5 mg/500 mg) dose administration under fasting
conditions.
Efficacy and Safety of Dapagliflozin in Combination With Metformin in Type 2 Diabetes Patients
Completed
Bristol-Myers Squibb
Phase 3
2008-03-01
This study is being carried out to see if dapagliflozin as an addition to metformin is
effective and safe in treating patients with type 2 diabetes when compared to glipizide
(sulphonylurea) as an addition to metformin treatment.
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