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Last Updated: November 11, 2024

CLINICAL TRIALS PROFILE FOR GEMTUZUMAB OZOGAMICIN


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All Clinical Trials for Gemtuzumab Ozogamicin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00003131 ↗ CMA-676 in Treating Patients With Acute Myeloid Leukemia in First Relapse Completed Pfizer Phase 2 1997-02-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of CMA-676 in treating patients with acute myeloid leukemia in first relapse.
NCT00003673 ↗ CMA-676 in Treating Older Patients With Acute Myeloid Leukemia in First Relapse Completed Pfizer Phase 2 1998-03-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of CMA-676 in treating older patients who have acute myeloid leukemia that has recurred for the first time following at least 3 months of complete remission.
NCT00005962 ↗ Comparison of Three Treatment Regimens in Treating Patients With Relapsed or Refractory Acute Myelogenous Leukemia Completed National Cancer Institute (NCI) Phase 2 2000-07-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies such as gemtuzumab ozogamicin can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining more than one drug or combining monoclonal antibody with chemotherapy may kill more cancer cells. It is not yet known which treatment regimen is more effective for acute myelogenous leukemia. PURPOSE: Randomized phase II trial to compare the effectiveness of three treatment regimens in treating patients who have relapsed or refractory acute myelogenous leukemia.
NCT00005962 ↗ Comparison of Three Treatment Regimens in Treating Patients With Relapsed or Refractory Acute Myelogenous Leukemia Completed Eastern Cooperative Oncology Group Phase 2 2000-07-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies such as gemtuzumab ozogamicin can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining more than one drug or combining monoclonal antibody with chemotherapy may kill more cancer cells. It is not yet known which treatment regimen is more effective for acute myelogenous leukemia. PURPOSE: Randomized phase II trial to compare the effectiveness of three treatment regimens in treating patients who have relapsed or refractory acute myelogenous leukemia.
NCT00006122 ↗ Gemtuzumab Ozogamicin With or Without Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia Completed European Organisation for Research and Treatment of Cancer - EORTC Phase 2 2000-06-01 RATIONALE: Monoclonal antibodies such as gemtuzumab ozogamicin can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy uses different ways to stop cancer cells from dividing so they stop growing or die. Combining gemtuzumab ozogamicin with chemotherapy may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of gemtuzumab ozogamicin with or without chemotherapy in treating older patients who have acute myeloid leukemia.
NCT00006265 ↗ Gemtuzumab Ozogamicin and High-Dose Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia Completed National Cancer Institute (NCI) Phase 2 2001-03-01 RATIONALE: Monoclonal antibodies, such as gemtuzumab ozogamicin, can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy, such as cytarabine, use different ways to stop cancer cells from dividing so they stop growing or die. Combining gemtuzumab ozogamicin with cytarabine may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining gemtuzumab ozogamicin with high-dose cytarabine in treating patients who have relapsed or refractory acute myeloid leukemia.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Gemtuzumab Ozogamicin

Condition Name

Condition Name for Gemtuzumab Ozogamicin
Intervention Trials
Acute Myeloid Leukemia 36
Leukemia 24
Myelodysplastic Syndrome 11
Acute Myelogenous Leukemia 9
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Condition MeSH

Condition MeSH for Gemtuzumab Ozogamicin
Intervention Trials
Leukemia 86
Leukemia, Myeloid, Acute 84
Leukemia, Myeloid 80
Myelodysplastic Syndromes 22
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Clinical Trial Locations for Gemtuzumab Ozogamicin

Trials by Country

Trials by Country for Gemtuzumab Ozogamicin
Location Trials
United States 491
Canada 33
Germany 15
United Kingdom 11
Australia 9
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Trials by US State

Trials by US State for Gemtuzumab Ozogamicin
Location Trials
New York 23
Texas 23
California 21
Washington 19
Michigan 18
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Clinical Trial Progress for Gemtuzumab Ozogamicin

Clinical Trial Phase

Clinical Trial Phase for Gemtuzumab Ozogamicin
Clinical Trial Phase Trials
Phase 4 2
Phase 3 16
Phase 2/Phase 3 5
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Clinical Trial Status

Clinical Trial Status for Gemtuzumab Ozogamicin
Clinical Trial Phase Trials
Completed 46
Recruiting 26
Terminated 6
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Clinical Trial Sponsors for Gemtuzumab Ozogamicin

Sponsor Name

Sponsor Name for Gemtuzumab Ozogamicin
Sponsor Trials
National Cancer Institute (NCI) 31
Pfizer 16
M.D. Anderson Cancer Center 10
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Sponsor Type

Sponsor Type for Gemtuzumab Ozogamicin
Sponsor Trials
Other 107
Industry 37
NIH 31
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