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Last Updated: January 21, 2020

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CLINICAL TRIALS PROFILE FOR GASTROGRAFIN

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All Clinical Trials for Gastrografin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00389116 Value of CT-Scan and Oral Gastrografin in the Management of Post Operative Small Bowel Obstruction Completed University Hospital, Rouen Phase 4 2006-11-01 Small bowel obstructions are responsible for 2 to 5% of emergency hospital admissions and 20% of all emergency surgical procedures. In 60 to 80% of cases, acute small bowel obstructions are the consequence of intraperitoneal postoperative adhesions. They constitute an extremely frequent pathology, leading to a high rate of hospital admissions and money expense. Management of small bowel obstruction is based on 2 options: either a surgical approach where all patients are operating on, or a conservative treatment in which surgery is proposed in case of failure of medical treatment. The surgical approach leads to operate on an excessive rate of patients while the medical approach increases the risk of increased small bowel resection, morbidity rate or hospitalization duration. In order to improve the management of small bowel obstruction, it seems necessary to better distinguish patients that need an emergency surgical procedure from patients in which medical treatment will be useful. Many studies have been performed to investigate the value of imaging in the management of small bowel obstruction, using abdominal X-ray, oral gastrografin administration or CT-Scan. The aim of this study is to analyse the effect of a systematic performance of imaging investigation on the management of patients presenting with a postoperative small bowel obstruction. All patients suffering from a postoperative small bowel obstruction will be included in this study. They will be randomised in 2 groups. In group S, patients will have CT-Scan and oral water administration while in group SG, Patients will have CT-Scan and oral gastrografin administration The major end point of this study is to analyse whether imaging examination can reduce the need for a surgical approach or the rate of small bowel resection and to determine its influence on fasting time or hospitalization duration
NCT00601809 (Gastrografin Use in Small Bowel Obstruction Caused by Adherences) Completed University of Bologna Phase 4 2003-09-01 Adhesive small intestine obstruction (ASIO) is an important cause of hospital admission and a very common disease. Any improvement in this field will benefit many patients by reducing the operative rate. Patients with this disease are difficult to evaluate and to manage and their treatment is controversial. Emergency surgery is mandatory when strangulation is suspected or in the case of total obstruction. On the other hand, conservative non-operative treatment is indicated in the case of partial obstruction. The role of water-soluble contrast medium (Gastrografin®: GG) in ASIO is still debated with regard to the therapeutic value. The aim of our study was to determine the therapeutic role of Gastrografin in patients with small intestine obstruction without strangulation caused by adherences (ASIO).
NCT01440712 Study of the Effect of Water Soluble Oral Contrast (Gastrografin) on Postoperative Ileus After Colorectal Surgery Completed Hospital Universitari de Bellvitge Phase 4 2011-12-01 The purpose of this trial is to determine whether the water-soluble contrast (gastrografin) is more effective in the treatment of postoperative ileus than the conventional one.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Gastrografin

Condition Name

Condition Name for Gastrografin
Intervention Trials
Small Bowel Obstruction 2
Postoperative Ileus 1
Adhesive Small Intestine Obstruction 1
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Condition MeSH

Condition MeSH for Gastrografin
Intervention Trials
Intestinal Obstruction 4
Ileus 2
Colorectal Neoplasms 1
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Clinical Trial Locations for Gastrografin

Trials by Country

Trials by Country for Gastrografin
Location Trials
Spain 2
China 1
Italy 1
Korea, Republic of 1
France 1
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Clinical Trial Progress for Gastrografin

Clinical Trial Phase

Clinical Trial Phase for Gastrografin
Clinical Trial Phase Trials
Phase 4 5
Phase 2/Phase 3 2
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Gastrografin
Clinical Trial Phase Trials
Completed 6
Not yet recruiting 2
Active, not recruiting 1
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Clinical Trial Sponsors for Gastrografin

Sponsor Name

Sponsor Name for Gastrografin
Sponsor Trials
Lawson Health Research Institute 2
University of Auckland, New Zealand 1
Nadja Haiden,MD 1
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Sponsor Type

Sponsor Type for Gastrografin
Sponsor Trials
Other 9
Industry 1
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