Comparison of Gadovist 75% Standard Dose to Dotarem at Full Standard Dose
The study was conducted to gain knowledge about a new dose of a diagnostic drug that is used
for contrast-enhanced Magnetic Resonance Imaging (MRI) of the human central nervous system
(CNS). MRI can visualize the anatomy of the body and is used to detect medical conditions.
Diagnostic drugs like gadobutrol and gadoterate contain an element called gadolinium that is
applied to improve the analysability of MRI-images.
The purpose of this study was to examine if contrast-enhanced MRI using a reduced dose of the
gadolinium-based contrast agent gadobutrol delivers images of similar quality to those
obtained when a full dose of the gadolinium-based contrast agent gadoterate was used.
Combined 18F-NaF/18F-FDG PET/MRI for Detection of Skeletal Metastases
This clinical trial studies the use of sodium fluorine-18 (18F-NaF) plus fluorine-18 (18F)
fluorodeoxyglucose (FDG) positron emission tomography (PET)/ whole body magnetic resonance
imaging (WBMRI) to detect skeletal metastases in patients with stage III-IV breast cancer or
stage II-IV prostate cancer.
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