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Generated: December 14, 2018

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CLINICAL TRIALS PROFILE FOR FLUOXETINE HYDROCHLORIDE; OLANZAPINE

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Clinical Trials for Fluoxetine Hydrochloride; Olanzapine

Trial ID Title Status Sponsor Phase Summary
NCT00000373 Treatment of Obsessive-Compulsive Disorder Completed National Institute of Mental Health (NIMH) Phase 4 The purpose of this study is to find the best treatment for Tourette's Syndrome (TS)-spectrum obsessive-compulsive disorder (OCD), which includes symptoms of TS, e.g., repeated and involuntary body movements (tics). There are 2 parts to this study: In Part 1, patients are placed into 1 of 2 groups based on type of OCD, determined by medical history and family member interviews. In Part 2, patients are treated with fluvoxamine (FVX) for 8 weeks. If patients do not respond to FVX alone, either haloperidol or an inactive placebo will be added to the FVX regimen; patients will take this drug combination for 4 weeks. Patients will be monitored throughout the trial.
NCT00000373 Treatment of Obsessive-Compulsive Disorder Completed University of Florida Phase 4 The purpose of this study is to find the best treatment for Tourette's Syndrome (TS)-spectrum obsessive-compulsive disorder (OCD), which includes symptoms of TS, e.g., repeated and involuntary body movements (tics). There are 2 parts to this study: In Part 1, patients are placed into 1 of 2 groups based on type of OCD, determined by medical history and family member interviews. In Part 2, patients are treated with fluvoxamine (FVX) for 8 weeks. If patients do not respond to FVX alone, either haloperidol or an inactive placebo will be added to the FVX regimen; patients will take this drug combination for 4 weeks. Patients will be monitored throughout the trial.
NCT00035321 The Study of Olanzapine Plus Fluoxetine in Combination for Treatment of Treatment Resistant Depression Completed Eli Lilly and Company Phase 3 The purposes of this study are to determine: - Whether olanzapine plus fluoxetine in combination will help patients with treatment-resistant major depression. - The safety of olanzapine plus fluoxetine in combination, plus and any side effects that might be associated with the combination. - The effectiveness of olanzapine plus fluoxetine compared to olanzapine and fluoxetine alone.
NCT00188942 A Neuroimaging Investigation of Brain Activity in Major Depressive Disorder and Bipolar Disorder Completed Eli Lilly and Company Phase 4 This study employs functional magnetic resonance imaging to compare brain activation patterns during a depressive episode in patients diagnosed with bipolar disorder, major depressive disorder, and a group of healthy control subjects. Depressed patients will be treated with a combination of fluoxetine and olanzapine and undergo MRI scans before, during, and after pharmacotherapy.
NCT00188942 A Neuroimaging Investigation of Brain Activity in Major Depressive Disorder and Bipolar Disorder Completed University Health Network, Toronto Phase 4 This study employs functional magnetic resonance imaging to compare brain activation patterns during a depressive episode in patients diagnosed with bipolar disorder, major depressive disorder, and a group of healthy control subjects. Depressed patients will be treated with a combination of fluoxetine and olanzapine and undergo MRI scans before, during, and after pharmacotherapy.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Fluoxetine Hydrochloride; Olanzapine

Condition Name

Condition Name for Fluoxetine Hydrochloride; Olanzapine
Intervention Trials
Major Depressive Disorder 2
Bipolar Disorder 2
Treatment Resistant Depression 2
Bipolar Depression 2
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Condition MeSH

Condition MeSH for Fluoxetine Hydrochloride; Olanzapine
Intervention Trials
Depression 9
Depressive Disorder 8
Bipolar Disorder 5
Depressive Disorder, Treatment-Resistant 4
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Clinical Trial Locations for Fluoxetine Hydrochloride; Olanzapine

Trials by Country

Trials by Country for Fluoxetine Hydrochloride; Olanzapine
Location Trials
United States 45
Canada 5
Puerto Rico 2
Russian Federation 2
India 1
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Trials by US State

Trials by US State for Fluoxetine Hydrochloride; Olanzapine
Location Trials
Pennsylvania 3
California 3
Massachusetts 2
New York 2
Florida 2
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Clinical Trial Progress for Fluoxetine Hydrochloride; Olanzapine

Clinical Trial Phase

Clinical Trial Phase for Fluoxetine Hydrochloride; Olanzapine
Clinical Trial Phase Trials
Phase 4 7
Phase 3 3
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Fluoxetine Hydrochloride; Olanzapine
Clinical Trial Phase Trials
Completed 10
Terminated 1
Not yet recruiting 1
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Clinical Trial Sponsors for Fluoxetine Hydrochloride; Olanzapine

Sponsor Name

Sponsor Name for Fluoxetine Hydrochloride; Olanzapine
Sponsor Trials
Eli Lilly and Company 7
GlaxoSmithKline 1
National Alliance on Mental Illness 1
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Sponsor Type

Sponsor Type for Fluoxetine Hydrochloride; Olanzapine
Sponsor Trials
Other 11
Industry 8
NIH 1
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Serving hundreds of leading biopharmaceutical companies globally:

McKesson
Cantor Fitzgerald
Baxter
Medtronic
Chinese Patent Office
Colorcon
Mallinckrodt
Fish and Richardson
Teva

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