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Last Updated: May 19, 2022

CLINICAL TRIALS PROFILE FOR FLUOROMETHOLONE


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All Clinical Trials for Fluorometholone

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00707421 ↗ Usefulness of Topical Non-Steroidal Anti-Inflammatory Drugs or Steroids Before Trabeculectomy and Clinical Outcomes Completed Funding for Research in Ophthalmology (FRO) Phase 3 2005-07-01 Antiglaucoma medication have been shown to induce subclinical conjunctival inflammation in a considerable proportion of glaucoma patients. Today, trabeculectomy still remains the gold standard as surgical treatment of medically uncontrolled glaucoma disease. However, this procedure is associated with variable possible complications, of which subconjunctival fibrosis is the most frequent one. The latter results in a non-functional filtering bleb. As a consequence, either additional interventions such as laser suture lysis, needling, bleb revision or additional IOP-lowering medication is necessary. Previous studies demonstrated a benefit of the use of topical steroids postoperatively in reducing inflammation and subsequent subconjunctival fibrosis. In this perspective, we will prospectively explore the usefulness of topical NSAID or corticosteroid therapy preoperatively as compared to placebo in subjects scheduled for first-time trabeculectomy, without interrupting topical antiglaucoma therapy. This will allow us to determine wether the impact of longterm topical antiglaucoma therapy on subclinical conjunctival inflammation which possibly result in postoperative fibrosis and bleb failure can be reversed by anti-inflammatory medication before filtering surgery.
NCT00707421 ↗ Usefulness of Topical Non-Steroidal Anti-Inflammatory Drugs or Steroids Before Trabeculectomy and Clinical Outcomes Completed Universitaire Ziekenhuizen Leuven Phase 3 2005-07-01 Antiglaucoma medication have been shown to induce subclinical conjunctival inflammation in a considerable proportion of glaucoma patients. Today, trabeculectomy still remains the gold standard as surgical treatment of medically uncontrolled glaucoma disease. However, this procedure is associated with variable possible complications, of which subconjunctival fibrosis is the most frequent one. The latter results in a non-functional filtering bleb. As a consequence, either additional interventions such as laser suture lysis, needling, bleb revision or additional IOP-lowering medication is necessary. Previous studies demonstrated a benefit of the use of topical steroids postoperatively in reducing inflammation and subsequent subconjunctival fibrosis. In this perspective, we will prospectively explore the usefulness of topical NSAID or corticosteroid therapy preoperatively as compared to placebo in subjects scheduled for first-time trabeculectomy, without interrupting topical antiglaucoma therapy. This will allow us to determine wether the impact of longterm topical antiglaucoma therapy on subclinical conjunctival inflammation which possibly result in postoperative fibrosis and bleb failure can be reversed by anti-inflammatory medication before filtering surgery.
NCT00824811 ↗ Topical Cyclosporine vs. Placebo for Epiphora Associated With Docetaxel Withdrawn Allergan Phase 2 2009-06-01 Objective: To evaluate the safety and efficacy of topical cyclosporine eye drops (Restasis®) for the treatment of epiphora caused by canalicular stenosis secondary to Docetaxel (Taxotere®) treatment for various cancers.
NCT00824811 ↗ Topical Cyclosporine vs. Placebo for Epiphora Associated With Docetaxel Withdrawn M.D. Anderson Cancer Center Phase 2 2009-06-01 Objective: To evaluate the safety and efficacy of topical cyclosporine eye drops (Restasis®) for the treatment of epiphora caused by canalicular stenosis secondary to Docetaxel (Taxotere®) treatment for various cancers.
NCT01288404 ↗ Randomized Controlled Trial of Subconjunctival Bevacizumab Injection in Impending Recurrent Pterygium Completed Ramathibodi Hospital N/A 2008-01-01 Hypothesis: Subconjunctival bevacizumab injection may potentially suppress neovascularization in pterygium, preventing or retarding the progression of recurrence.
NCT01448213 ↗ Comparison of Two Steroid Regimens to Prevent Transplant Rejection After Corneal Transplant (DMEK) Completed Price Vision Group Phase 2 2011-10-01 The purpose of this study is to compare two different commonly used steroid dosing regimens after Descemet's membrane endothelial keratoplasty (DMEK) transplant surgery. The investigators hope to determine if one is more effective at preventing rejection or if both are equally effective.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Fluorometholone

Condition Name

Condition Name for Fluorometholone
Intervention Trials
Intraocular Pressure 3
Trichiasis 2
Ocular Rosacea 1
Adenoviral Keratoconjunctivitis 1
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Condition MeSH

Condition MeSH for Fluorometholone
Intervention Trials
Keratoconjunctivitis Sicca 3
Eye Diseases 3
Dry Eye Syndromes 3
Keratoconjunctivitis 3
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Clinical Trial Locations for Fluorometholone

Trials by Country

Trials by Country for Fluorometholone
Location Trials
China 4
United States 3
Ethiopia 2
Egypt 2
Germany 1
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Trials by US State

Trials by US State for Fluorometholone
Location Trials
Indiana 2
Utah 1
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Clinical Trial Progress for Fluorometholone

Clinical Trial Phase

Clinical Trial Phase for Fluorometholone
Clinical Trial Phase Trials
Phase 4 7
Phase 3 3
Phase 2 4
[disabled in preview] 6
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Clinical Trial Status

Clinical Trial Status for Fluorometholone
Clinical Trial Phase Trials
Completed 11
Unknown status 3
Not yet recruiting 3
[disabled in preview] 3
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Clinical Trial Sponsors for Fluorometholone

Sponsor Name

Sponsor Name for Fluorometholone
Sponsor Trials
Price Vision Group 2
Berhan Public Health and Eye Care Consultancy PLC 2
Zhongshan Ophthalmic Center, Sun Yat-sen University 2
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Sponsor Type

Sponsor Type for Fluorometholone
Sponsor Trials
Other 32
Industry 4
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