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Last Updated: October 23, 2019

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CLINICAL TRIALS PROFILE FOR FERAHEME

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Clinical Trials for Feraheme

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00103038 Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases Active, not recruiting National Cancer Institute (NCI) N/A 2004-02-01 This clinical trial studies magnetic resonance imaging (MRI) using a contrast imaging agent ferumoxytol (ferumoxytol non-stoichiometric magnetite) in improving viewing tumors in patients with high-grade brain tumors or cancer that has spread to the brain. Diagnostic procedures, such as MRI, may help find and diagnose brain tumors and find out how far the disease has spread. The contrast imaging agent ferumoxytol non-stoichiometric magnetite consists of small iron particles taken by the blood stream to the brain and to the area of the tumor. It may help visualize the blood flow going through the tumor better than the standard substance gadolinium-based contrast agent.
NCT00103038 Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases Active, not recruiting OHSU Knight Cancer Institute N/A 2004-02-01 This clinical trial studies magnetic resonance imaging (MRI) using a contrast imaging agent ferumoxytol (ferumoxytol non-stoichiometric magnetite) in improving viewing tumors in patients with high-grade brain tumors or cancer that has spread to the brain. Diagnostic procedures, such as MRI, may help find and diagnose brain tumors and find out how far the disease has spread. The contrast imaging agent ferumoxytol non-stoichiometric magnetite consists of small iron particles taken by the blood stream to the brain and to the area of the tumor. It may help visualize the blood flow going through the tumor better than the standard substance gadolinium-based contrast agent.
NCT00659126 Ferumoxytol- and Gadolinium-Labeled MRI in Measuring Tumors Before or After Treatment in Patients With Primary or Metastatic Brain Tumors Recruiting National Cancer Institute (NCI) Phase 2 2006-11-01 This phase II trial studies how well magnetic resonance imaging (MRI) using contrast imaging agent ferumoxytol works in comparison to standard imaging agent gadolinium in measuring tumors in patients undergoing treatment for brain tumors or other tumors that have spread to the brain. Diagnostic procedures, such as MRI, may help find and diagnose disease and find out how far the disease has spread. MRI scans use radio waves and a powerful magnet linked to a computer to create detailed pictures of areas inside the body. The contrast imaging agent ferumoxytol consists of small iron particles taken by the blood stream to the brain and to the area of the tumor. It is highly visible on the MRI, and may help visualize the blood flow going through the tumor better than gadolinium can. Using a more sensitive and faster 7 Tesla (7T) magnet MRI in conjunction with a contrast imaging agent may provide a better way to measure tumors than the 3 Tesla (3T) magnet MRI in patients with brain tumors.
NCT00659126 Ferumoxytol- and Gadolinium-Labeled MRI in Measuring Tumors Before or After Treatment in Patients With Primary or Metastatic Brain Tumors Recruiting OHSU Knight Cancer Institute Phase 2 2006-11-01 This phase II trial studies how well magnetic resonance imaging (MRI) using contrast imaging agent ferumoxytol works in comparison to standard imaging agent gadolinium in measuring tumors in patients undergoing treatment for brain tumors or other tumors that have spread to the brain. Diagnostic procedures, such as MRI, may help find and diagnose disease and find out how far the disease has spread. MRI scans use radio waves and a powerful magnet linked to a computer to create detailed pictures of areas inside the body. The contrast imaging agent ferumoxytol consists of small iron particles taken by the blood stream to the brain and to the area of the tumor. It is highly visible on the MRI, and may help visualize the blood flow going through the tumor better than gadolinium can. Using a more sensitive and faster 7 Tesla (7T) magnet MRI in conjunction with a contrast imaging agent may provide a better way to measure tumors than the 3 Tesla (3T) magnet MRI in patients with brain tumors.
NCT00659776 MR, Histologic And EM Imaging Of Intravenous Ferumoxytol In Central Nervous System (CNS) Inflammation Unknown status National Institute of Neurological Disorders and Stroke (NINDS) Phase 2 2004-07-01 The purpose of this study is to address safety and efficiency of a new iron particle contrast agent, ferumoxytol. This product may be more useful in viewing the vessels of the brain and areas in the brain on magnetic resonance imaging (MRI), or magnetic resonance angiography (MRA), than the standard substance, gadolinium, injected during MRI and MRA. Other ways in which ferumoxytol may help include the following: 1. Ferumoxytol may provide the ability to better see inflammatory lesions on magnetic resonance imaging (MRI) scans 2. Ferumoxytol may be useful in its ability to cross blood vessels into inflammatory processes, and 3. Ferumoxytol, because of its size and ability to get into the area next to your inflammatory lesion and could assist in the treatment of inflammatory lesions association with cardiac surgery or CNS vascular surgery.
NCT00659776 MR, Histologic And EM Imaging Of Intravenous Ferumoxytol In Central Nervous System (CNS) Inflammation Unknown status Oregon Health and Science University Phase 2 2004-07-01 The purpose of this study is to address safety and efficiency of a new iron particle contrast agent, ferumoxytol. This product may be more useful in viewing the vessels of the brain and areas in the brain on magnetic resonance imaging (MRI), or magnetic resonance angiography (MRA), than the standard substance, gadolinium, injected during MRI and MRA. Other ways in which ferumoxytol may help include the following: 1. Ferumoxytol may provide the ability to better see inflammatory lesions on magnetic resonance imaging (MRI) scans 2. Ferumoxytol may be useful in its ability to cross blood vessels into inflammatory processes, and 3. Ferumoxytol, because of its size and ability to get into the area next to your inflammatory lesion and could assist in the treatment of inflammatory lesions association with cardiac surgery or CNS vascular surgery.
NCT00660543 MRI Study With Ferumoxytol in Assessing Early Response in Patients With Glioblastoma Multiforme Receiving Temozolomide and Radiation Therapy Completed National Cancer Institute (NCI) N/A 2006-12-01 This pilot clinical trial studies how a magnetic resonance imaging (MRI) study with ferumoxytol works as a contrasting agent in assessing early response in patients with glioblastoma multiforme receiving temozolomide and radiation therapy. Ferumoxytol is a very small form of iron particles that are injected into the body and taken up by certain tissues which may make these tissues easier to see during imaging. Diagnostic procedures, such as an MRI study with ferumoxytol, may help measure a patient's response to earlier treatment.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Feraheme

Condition Name

Condition Name for Feraheme
Intervention Trials
Iron Deficiency Anemia 8
Childhood Brain Neoplasm 3
Metastatic Malignant Neoplasm in the Brain 3
Anemia 3
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Condition MeSH

Condition MeSH for Feraheme
Intervention Trials
Anemia, Iron-Deficiency 13
Anemia 12
Deficiency Diseases 11
Brain Neoplasms 7
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Clinical Trial Locations for Feraheme

Trials by Country

Trials by Country for Feraheme
Location Trials
United States 41
Canada 2
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Trials by US State

Trials by US State for Feraheme
Location Trials
Massachusetts 12
Oregon 10
California 5
Maryland 3
Texas 2
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Clinical Trial Progress for Feraheme

Clinical Trial Phase

Clinical Trial Phase for Feraheme
Clinical Trial Phase Trials
Phase 4 8
Phase 3 8
Phase 2 9
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Clinical Trial Status

Clinical Trial Status for Feraheme
Clinical Trial Phase Trials
Recruiting 13
Completed 9
Not yet recruiting 6
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Clinical Trial Sponsors for Feraheme

Sponsor Name

Sponsor Name for Feraheme
Sponsor Trials
National Cancer Institute (NCI) 15
AMAG Pharmaceuticals, Inc. 13
OHSU Knight Cancer Institute 10
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Sponsor Type

Sponsor Type for Feraheme
Sponsor Trials
Other 35
NIH 18
Industry 15
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