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Last Updated: July 13, 2020

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CLINICAL TRIALS PROFILE FOR ESKETAMINE HYDROCHLORIDE

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All Clinical Trials for Esketamine Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00847418 Pharmacokinetics and Pharmacodynamics of Nasally Applied Esketamine Completed University Hospital, Basel, Switzerland Phase 1 2009-02-01 The purpose of this study is the determination of blood concentration and the effectiveness of esketamine after nasal application.
NCT01640080 A Study of the Efficacy of Intravenous Esketamine in Adult Patients With Treatment-Resistant Depression Completed Janssen Research & Development, LLC Phase 2 2012-06-01 The purpose of this study is to assess the efficacy of esketamine compared with placebo in improving symptoms of depression in patients with treatment resistant depression.
NCT01780259 A Study to Assess the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy Participants Completed Janssen Research & Development, LLC Phase 1 2012-12-01 The primary purpose of the study is to evaluate the pharmacokinetics (what the body does to the medication) of intranasally (through the nose) administered esketamine in healthy participants.
NCT01980303 A Study to Assess the Pharmacokinetics of Intranasally Administered Esketamine in Healthy Japanese and Caucasian Volunteers Completed Janssen Research & Development, LLC Phase 1 2013-11-01 The purpose of this Phase 1 study is to characterize the pharmacokinetic profile (what the body does to the medication) of esketamine when given by the intranasal route (through the nose) to healthy adult Japanese and Caucasian participants.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Esketamine Hydrochloride

Condition Name

Condition Name for Esketamine Hydrochloride
Intervention Trials
Healthy 14
Depressive Disorder, Treatment-Resistant 5
Depressive Disorder, Major 5
Major Depressive Disorder 4
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Condition MeSH

Condition MeSH for Esketamine Hydrochloride
Intervention Trials
Depression 23
Depressive Disorder 22
Depressive Disorder, Treatment-Resistant 13
Depressive Disorder, Major 9
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Clinical Trial Locations for Esketamine Hydrochloride

Trials by Country

Trials by Country for Esketamine Hydrochloride
Location Trials
United States 193
Belgium 17
Poland 13
Canada 12
Germany 10
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Trials by US State

Trials by US State for Esketamine Hydrochloride
Location Trials
New York 12
California 12
Maryland 11
Texas 10
Ohio 10
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Clinical Trial Progress for Esketamine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Esketamine Hydrochloride
Clinical Trial Phase Trials
Phase 4 2
Phase 3 12
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Esketamine Hydrochloride
Clinical Trial Phase Trials
Completed 18
Recruiting 18
Not yet recruiting 11
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Clinical Trial Sponsors for Esketamine Hydrochloride

Sponsor Name

Sponsor Name for Esketamine Hydrochloride
Sponsor Trials
Janssen Research & Development, LLC 32
Celon Pharma SA 3
Janssen-Cilag International NV 2
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Sponsor Type

Sponsor Type for Esketamine Hydrochloride
Sponsor Trials
Industry 38
Other 12
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