CLINICAL TRIALS PROFILE FOR ERAVACYCLINE DIHYDROCHLORIDE
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All Clinical Trials for Eravacycline Dihydrochloride
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT01265784 ↗ | Study to Compare TP-434 and Ertapenem in Community-acquired Complicated Intra-abdominal Infections | Completed | Tetraphase Pharmaceuticals, Inc. | Phase 2 | 2011-01-01 | This is a Phase 2, randomized, double-blind, double-dummy, multicenter, prospective study to assess the efficacy, safety, and pharmacokinetics of two dose regimens of TP-434 compared with ertapenem in the treatment of adult community-acquired complicated intra-abdominal infections (cIAIs). |
| NCT01844856 ↗ | Efficacy and Safety Study of Eravacycline Compared With Ertapenem in Complicated Intra-abdominal Infections | Completed | Tetraphase Pharmaceuticals, Inc. | Phase 3 | 2013-08-01 | This is a Phase 3, randomized, double-blind, double-dummy, multicenter, prospective study to assess the efficacy, safety, and pharmacokinetics of eravacycline compared with ertapenem in the treatment of adult complicated intra-abdominal infections (cIAI). |
| NCT01941446 ↗ | A Thorough QT/QTc Study to Evaluate the Effects of an Intravenous Infusion of Eravacycline (TP-434) on Cardiac Repolarization | Completed | Tetraphase Pharmaceuticals, Inc. | Phase 1 | 2013-03-01 | This is a randomized, placebo- and positive-controlled (moxifloxacin), 3-period, 3-way crossover thorough QT study, which includes a Screening Period, Treatment Periods (1 through 3), and a Follow-up Visit. Subjects will be confined to the investigational site for 4 nights/3 days during Period 1 and for 3 nights/2 days during Periods 2 and 3. There will be a minimum of a 14 day washout between treatments. |
| NCT01978938 ↗ | Efficacy and Safety Study of Eravacycline Compared With Levofloxacin in Complicated Urinary Tract Infections | Completed | Tetraphase Pharmaceuticals, Inc. | Phase 3 | 2014-10-06 | This is a phase 3, randomized, double-blind, double-dummy, multicenter, prospective study to assess the efficacy and safety of eravacycline compared with levofloxacin in participants with complicated urinary tract infections (cUTI). |
| NCT01989949 ↗ | Safety and Pharmacokinetic (PK) Study to Assess Bronchopulmonary Disposition of IV Eravacycline (TP-434) in Healthy Men and Women | Completed | Department of Health and Human Services | Phase 1 | 2012-11-01 | This is a phase 1, open-label, randomized pharmacokinetic and safety study in healthy adult subjects, who will undergo bronchoscopy and bronchoalveolar lavage (BAL) after receiving seven (7) doses of 1.0 mg/kg IV TP-434. |
| NCT01989949 ↗ | Safety and Pharmacokinetic (PK) Study to Assess Bronchopulmonary Disposition of IV Eravacycline (TP-434) in Healthy Men and Women | Completed | Tetraphase Pharmaceuticals, Inc. | Phase 1 | 2012-11-01 | This is a phase 1, open-label, randomized pharmacokinetic and safety study in healthy adult subjects, who will undergo bronchoscopy and bronchoalveolar lavage (BAL) after receiving seven (7) doses of 1.0 mg/kg IV TP-434. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for Eravacycline Dihydrochloride
Condition Name
| Condition Name for Eravacycline Dihydrochloride | |
| Intervention | Trials |
| Complicated Intra-abdominal Infections | 2 |
| Complicated Intra-abdominal Infection | 1 |
| Complicated Urinary Tract Infections | 1 |
| Complicated Urinary Tract Infections (cUTI) | 1 |
| [disabled in preview] | 0 |
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Clinical Trial Locations for Eravacycline Dihydrochloride
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Clinical Trial Progress for Eravacycline Dihydrochloride
Clinical Trial Phase
Clinical Trial Sponsors for Eravacycline Dihydrochloride
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