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Generated: February 19, 2019

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CLINICAL TRIALS PROFILE FOR ENTEREG

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Clinical Trials for Entereg

Trial ID Title Status Sponsor Phase Summary
NCT00256932 Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain Completed GlaxoSmithKline Phase 3 Adults who are taking opioid therapy for persistent non-cancer pain and have resulting opioid-induced bowel dysfunction (OBD) will be randomized (1:1:1) to one 2 alvimopan arms, or to placebo. The primary objective of this phase 3 confirmatory study is to compare alvimopan with placebo for efficacy in the treatment of OBD. The primary efficacy endpoint is based on frequency of bowel movements. Subjects will be required to: (1) track their bowel movements and other bowel symptoms and (2) attend 6 clinic visits over 4 months.
NCT00256932 Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain Completed Cubist Pharmaceuticals LLC Phase 3 Adults who are taking opioid therapy for persistent non-cancer pain and have resulting opioid-induced bowel dysfunction (OBD) will be randomized (1:1:1) to one 2 alvimopan arms, or to placebo. The primary objective of this phase 3 confirmatory study is to compare alvimopan with placebo for efficacy in the treatment of OBD. The primary efficacy endpoint is based on frequency of bowel movements. Subjects will be required to: (1) track their bowel movements and other bowel symptoms and (2) attend 6 clinic visits over 4 months.
NCT00259922 Alvimopan For The Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain Completed GlaxoSmithKline Phase 3 Adults who are taking opioid therapy for persistent non-cancer pain and have resulting opioid-induced bowel dysfunction (OBD) will be randomized (1:1:1) to one of 2 alvimopan arms, or to placebo. The primary objective of this phase 3 confirmatory study is to compare alvimopan with placebo for efficacy in the treatment of OBD. The primary efficacy endpoint is based on frequency of bowel movements. Subjects will be required to: (1) track their bowel movements and other bowel symptoms and (2) attend 6 clinic visits over 4 months.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Entereg

Condition Name

Condition Name for Entereg
Intervention Trials
Ileus 5
Constipation 3
Colorectal Surgery 2
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Condition MeSH

Condition MeSH for Entereg
Intervention Trials
Ileus 5
Constipation 3
Intestinal Diseases 2
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Clinical Trial Locations for Entereg

Trials by Country

Trials by Country for Entereg
Location Trials
United States 92
Canada 12
Germany 8
United Kingdom 7
Australia 5
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Trials by US State

Trials by US State for Entereg
Location Trials
California 4
North Carolina 4
Ohio 4
Louisiana 3
Connecticut 3
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Clinical Trial Progress for Entereg

Clinical Trial Phase

Clinical Trial Phase for Entereg
Clinical Trial Phase Trials
Phase 4 3
Phase 3 5
Phase 2 2
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Clinical Trial Status

Clinical Trial Status for Entereg
Clinical Trial Phase Trials
Completed 7
Not yet recruiting 5
Recruiting 1
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Clinical Trial Sponsors for Entereg

Sponsor Name

Sponsor Name for Entereg
Sponsor Trials
Cubist Pharmaceuticals LLC 7
GlaxoSmithKline 3
Merck Sharp & Dohme Corp. 3
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Sponsor Type

Sponsor Type for Entereg
Sponsor Trials
Industry 13
Other 12
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Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
Accenture
Baxter
Chubb
Cipla
US Army
Queensland Health
Mallinckrodt
Teva

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