To compare the effects of nonpharmacologic therapy alone with those of one of five active
drug regimens combined with non-pharmacologic therapy, for long- term management of patients
with mild hypertension.
To compare the effects of nonpharmacologic therapy alone with those of one of five active
drug regimens combined with non-pharmacologic therapy, for long- term management of patients
with mild hypertension.
University of Minnesota - Clinical and Translational Science Institute
Phase 2
1985-08-01
To compare the effects of nonpharmacologic therapy alone with those of one of five active
drug regimens combined with non-pharmacologic therapy, for long- term management of patients
with mild hypertension.
Enalapril in Treating Heart Damage Patients Who Received Anthracycline Chemotherapy for Childhood Cancer
Completed
National Cancer Institute (NCI)
Phase 3
2000-09-01
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Chemoprotective drugs, such as enalapril, may protect normal cells
from the toxic effects of chemotherapy. It is not known whether enalapril is more effective
than a placebo in treating heart damage in patients who received anthracycline chemotherapy
for childhood cancer.
PURPOSE: Randomized double-blinded phase III trial to compare the effectiveness of enalapril
with a placebo in treating heart damage in patients who received anthracycline chemotherapy
for childhood cancer.
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