A Study Evaluating the Long-term Safety of VX-445 Combination Therapy
Active, not recruiting
Vertex Pharmaceuticals Incorporated
Phase 3
2019-08-09
This study will evaluate the long-term safety and tolerability of elexacaftor (ELX, VX-445)
in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA).
A Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)
Completed
Vertex Pharmaceuticals Incorporated
Phase 3
2019-08-28
This study will evaluate the efficacy, safety and pharmacodynamics of elexacaftor (ELX,
VX-445) in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects with
cystic fibrosis (CF) who are heterozygous for F508del and a gating or residual function
mutation (F/G and F/RF genotypes).
Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy
Active, not recruiting
Vertex Pharmaceuticals Incorporated
Phase 3
2019-12-05
This study will evaluate the long-term safety, efficacy, and pharmacodynamics of elexacaftor
(ELX, VX-445) in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in
subjects with cystic fibrosis (CF) who are heterozygous for the F508del mutation and a gating
or residual function mutation (F/G and F/RF genotypes).
A Study Evaluating the Efficacy and Safety of VX-445/Tezacaftor/Ivacaftor in Cystic Fibrosis Subjects, Homozygous for F508del
Completed
Vertex Pharmaceuticals Incorporated
Phase 3
2019-10-03
This study will evaluate the efficacy, safety, and pharmacodynamics of elexacaftor (ELX,
VX-445) in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects with
cystic fibrosis (CF) who are homozygous for F508del.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.
