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Last Updated: March 28, 2024

CLINICAL TRIALS PROFILE FOR EFLORNITHINE HYDROCHLORIDE


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All Clinical Trials for Eflornithine Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00003076 ↗ Eflornithine to Prevent Cancer in Patients With Barrett's Esophagus Completed National Cancer Institute (NCI) Phase 2 1995-10-01 RATIONALE: Chemoprevention therapy is the use of drugs to try and prevent the development or recurrence of cancer. It is not known whether eflornithine is effective in preventing cancer in patients with Barrett's esophagus. PURPOSE: Randomized double-blinded phase II trial to study the effectiveness of eflornithine in preventing cancer in patients with Barrett's esophagus.
NCT00003076 ↗ Eflornithine to Prevent Cancer in Patients With Barrett's Esophagus Completed University of Michigan Cancer Center Phase 2 1995-10-01 RATIONALE: Chemoprevention therapy is the use of drugs to try and prevent the development or recurrence of cancer. It is not known whether eflornithine is effective in preventing cancer in patients with Barrett's esophagus. PURPOSE: Randomized double-blinded phase II trial to study the effectiveness of eflornithine in preventing cancer in patients with Barrett's esophagus.
NCT00003076 ↗ Eflornithine to Prevent Cancer in Patients With Barrett's Esophagus Completed University of Michigan Rogel Cancer Center Phase 2 1995-10-01 RATIONALE: Chemoprevention therapy is the use of drugs to try and prevent the development or recurrence of cancer. It is not known whether eflornithine is effective in preventing cancer in patients with Barrett's esophagus. PURPOSE: Randomized double-blinded phase II trial to study the effectiveness of eflornithine in preventing cancer in patients with Barrett's esophagus.
NCT00003814 ↗ Eflornithine in Treating Patients With Bladder Cancer Completed National Cancer Institute (NCI) Phase 3 1999-02-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if eflornithine is more effective than no further therapy in treating bladder cancer. PURPOSE: Randomized phase III trial to determine the effectiveness of eflornithine in treating patients who have newly diagnosed or recurrent bladder cancer.
NCT00005882 ↗ Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps Completed Chao Family Comprehensive Cancer Center Phase 3 1998-07-01 This randomized phase III trial is studying eflornithine and sulindac to see how well they work compared to a placebo in preventing colorectal cancer in patients with colon polyps. Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of eflornithine and sulindac may prevent colorectal cancer. It is not yet known whether eflornithine and sulindac are more effective than a placebo in preventing colorectal cancer
NCT00005882 ↗ Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps Completed National Cancer Institute (NCI) Phase 3 1998-07-01 This randomized phase III trial is studying eflornithine and sulindac to see how well they work compared to a placebo in preventing colorectal cancer in patients with colon polyps. Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of eflornithine and sulindac may prevent colorectal cancer. It is not yet known whether eflornithine and sulindac are more effective than a placebo in preventing colorectal cancer
NCT00005882 ↗ Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps Completed University of California, Irvine Phase 3 1998-07-01 This randomized phase III trial is studying eflornithine and sulindac to see how well they work compared to a placebo in preventing colorectal cancer in patients with colon polyps. Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of eflornithine and sulindac may prevent colorectal cancer. It is not yet known whether eflornithine and sulindac are more effective than a placebo in preventing colorectal cancer
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Eflornithine Hydrochloride

Condition Name

Condition Name for Eflornithine Hydrochloride
Intervention Trials
Trypanosomiasis, African 5
Neuroblastoma 4
Sleeping Sickness 3
Non-melanomatous Skin Cancer 3
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Condition MeSH

Condition MeSH for Eflornithine Hydrochloride
Intervention Trials
Trypanosomiasis, African 7
Trypanosomiasis 7
Colorectal Neoplasms 6
Neuroblastoma 6
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Clinical Trial Locations for Eflornithine Hydrochloride

Trials by Country

Trials by Country for Eflornithine Hydrochloride
Location Trials
United States 268
Canada 13
Congo 10
Congo, The Democratic Republic of the 8
Germany 7
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Trials by US State

Trials by US State for Eflornithine Hydrochloride
Location Trials
California 13
Texas 13
Minnesota 11
Missouri 11
Florida 11
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Clinical Trial Progress for Eflornithine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Eflornithine Hydrochloride
Clinical Trial Phase Trials
Phase 4 3
Phase 3 10
Phase 2/Phase 3 4
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Clinical Trial Status

Clinical Trial Status for Eflornithine Hydrochloride
Clinical Trial Phase Trials
Completed 18
Recruiting 8
Active, not recruiting 4
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Clinical Trial Sponsors for Eflornithine Hydrochloride

Sponsor Name

Sponsor Name for Eflornithine Hydrochloride
Sponsor Trials
National Cancer Institute (NCI) 17
Giselle SaulnierSholler 6
Giselle Sholler 5
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Sponsor Type

Sponsor Type for Eflornithine Hydrochloride
Sponsor Trials
Other 64
NIH 17
Industry 13
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