CLINICAL TRIALS PROFILE FOR EDARAVONE
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All Clinical Trials for Edaravone
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00153946 ↗ | Edaravone and Argatroban Stroke Therapy Study for Acute Ischemic Stroke | Completed | Japan Cardiovascular Research Foundation | Phase 4 | 2004-08-01 | Edaravone, a free radical scavenger, is a novel neuroprotective agent, and argatroban is a selective thrombin inhibitor. Both the drugs were approved by the Japanese Government, and have frequently been used for the treatment of acute brain infarction in Japan. The effect of combination therapy of these drugs, however, has not yet been elucidated. This study will test the safety and efficacy of the combination therapy with these agents in patients with acute non-cardioembolic and non-lacunar ischemic stroke. |
| NCT00153946 ↗ | Edaravone and Argatroban Stroke Therapy Study for Acute Ischemic Stroke | Completed | Combination Therapy for Acute Ischemic Stroke Study Group | Phase 4 | 2004-08-01 | Edaravone, a free radical scavenger, is a novel neuroprotective agent, and argatroban is a selective thrombin inhibitor. Both the drugs were approved by the Japanese Government, and have frequently been used for the treatment of acute brain infarction in Japan. The effect of combination therapy of these drugs, however, has not yet been elucidated. This study will test the safety and efficacy of the combination therapy with these agents in patients with acute non-cardioembolic and non-lacunar ischemic stroke. |
| NCT00200356 ↗ | Edaravone-Sodium Ozagrel Comparative Post-Marketing Study on Acute Ischemic Stroke | Completed | Mitsubishi Tanabe Pharma Corporation | Phase 4 | 2004-08-01 | This study is randomized, Sodium Ozagrel (Thromboxane A2 Synthase Inhibitor) controlled study on acute ischemic stroke. The primary endpoints were the rate of patients with modified Rankin Scale score of 0-1 at 3 months. |
| NCT00265239 ↗ | Pilot Study of Edaravone to Treat Acute Myocardial Infarction | Completed | Japan Heart Foundation | Phase 4 | 2001-04-01 | Early reperfusion therapy has improved the clinical outcomes of patients with acute myocardial infarction (AMI), but these benefits are limited in some patients by reperfusion injuries. There is now increasing evidence that reactive oxygen species cause reperfusion injury. This study was designed to examine the effects of edaravone, a novel free radical scavenger, in patients with AMI. |
| NCT00265239 ↗ | Pilot Study of Edaravone to Treat Acute Myocardial Infarction | Completed | Kumamoto University | Phase 4 | 2001-04-01 | Early reperfusion therapy has improved the clinical outcomes of patients with acute myocardial infarction (AMI), but these benefits are limited in some patients by reperfusion injuries. There is now increasing evidence that reactive oxygen species cause reperfusion injury. This study was designed to examine the effects of edaravone, a novel free radical scavenger, in patients with AMI. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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