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Last Updated: March 28, 2024

CLINICAL TRIALS PROFILE FOR ELESTRIN


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All Clinical Trials for ELESTRIN

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01633814 ↗ Hormone Replacement and Neural Cardiovascular Control in Postmenopausal Women Terminated University of Missouri-Columbia N/A 2011-09-01 Older women have an exaggerated increase in blood pressure during exercise. However, the reasons for this are unclear. It is important to investigate this phenomenon because a greater blood pressure response to exercise has been associated with an increased risk of stroke and mortality in otherwise healthy individuals. A unique aspect of aging in women is the profound change in hormone levels (i.e. estrogen and progesterone) associated with menopause. The influence of changes in estrogen and progesterone levels on the cardiovascular responses to exercise is poorly understood. However, it has been suggested that these hormones might change the responsiveness of the cardiovascular system. Possible mechanisms that could account for these changes are the arterial baroreflex and feedback from the exercising muscle (known as the exercise pressor reflex), both of which are known to powerfully modulate blood pressure during exercise. However, to date, few human studies have thoroughly examined the influence of changes in hormone levels on baroreflex function during exercise or the exercise pressor reflex in older women. As such, the purpose of this research project is to assess baroreflex function and the exercise pressor reflex in older women after transdermal estrogen and placebo.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for ELESTRIN

Condition Name

Condition Name for ELESTRIN
Intervention Trials
Aging 1
Blood Pressure 1
Menopause 1
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Condition MeSH

Condition MeSH for ELESTRIN
Intervention Trials
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Clinical Trial Locations for ELESTRIN

Trials by Country

Trials by Country for ELESTRIN
Location Trials
United States 1
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Trials by US State

Trials by US State for ELESTRIN
Location Trials
Missouri 1
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Clinical Trial Progress for ELESTRIN

Clinical Trial Phase

Clinical Trial Phase for ELESTRIN
Clinical Trial Phase Trials
N/A 1
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Clinical Trial Status

Clinical Trial Status for ELESTRIN
Clinical Trial Phase Trials
Terminated 1
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Clinical Trial Sponsors for ELESTRIN

Sponsor Name

Sponsor Name for ELESTRIN
Sponsor Trials
University of Missouri-Columbia 1
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Sponsor Type

Sponsor Type for ELESTRIN
Sponsor Trials
Other 1
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