Clonidine as Adjunct Therapy for the Treatment of Neonatal Abstinence Syndrome
Completed
Johns Hopkins University
Phase 2
2002-07-01
To test the hypothesis that the combination of the tincture of opium (DTO) and clonidine will
be more effective in treating infants with neonatal abstinence syndrome (opioid withdrawal)
than tincture of opium (DTO) alone.
Clonidine as Adjunct Therapy for the Treatment of Neonatal Abstinence Syndrome
Completed
National Institute on Drug Abuse (NIDA)
Phase 2
2002-07-01
To test the hypothesis that the combination of the tincture of opium (DTO) and clonidine will
be more effective in treating infants with neonatal abstinence syndrome (opioid withdrawal)
than tincture of opium (DTO) alone.
Tonsillectomy is associated with a significant decrease quality of life in children secondary
to pain, which is worsened with swallowing. The objective of the current study is to conduct
a prospective, double-blind, placebo-controlled, randomized clinical trial using a
pre-tonsillectomy infiltration of the tonsillar fossa comparing three treatment regimens in
reducing post-tonsillectomy morbidity (i.e. pain, poor oral intake): 1) Placebo (saline
injection) 2) bupivacaine (0.5%) + lidocaine (1%), 3) bupivacaine (0.5%) + lidocaine (1%) +
clonidine (25 µg).
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models.
By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.
