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Generated: January 19, 2019

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CLINICAL TRIALS PROFILE FOR DIFLUNISAL

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Clinical Trials for Diflunisal

Trial ID Title Status Sponsor Phase Summary
NCT00294671 The Effect of Diflunisal on Familial Amyloidosis Completed Food and Drug Administration (FDA) Phase 2/Phase 3 The purpose of this study is to determine if diflunisal can prevent progressive lower leg nerve damage in patients with familial amyloidosis polyneuropathy. Funding Source - FDA OOPD; NINDS
NCT00294671 The Effect of Diflunisal on Familial Amyloidosis Completed National Institute of Neurological Disorders and Stroke (NINDS) Phase 2/Phase 3 The purpose of this study is to determine if diflunisal can prevent progressive lower leg nerve damage in patients with familial amyloidosis polyneuropathy. Funding Source - FDA OOPD; NINDS
NCT00294671 The Effect of Diflunisal on Familial Amyloidosis Completed Boston University Phase 2/Phase 3 The purpose of this study is to determine if diflunisal can prevent progressive lower leg nerve damage in patients with familial amyloidosis polyneuropathy. Funding Source - FDA OOPD; NINDS
NCT01432587 The Effect of Diflunisal on Familial Transthyretin Amyloidosis Completed Umeå University N/A An ongoing trial of diflunisal has been closed for enrollment, thus, patients suitable for the study can no longer participate or receive treatment by diflunisal; and patients, who have participated in the trial can not continue their treatment. The investigators want to continue to monitor the effect of the drug on transthyretin (TTR) amyloidosis in an open label observational study. Primary endpoint will be a composite score of the manifestations of the disease (Kumamoto scale) and secondary end points will be measurements of neurological impairment, heart involvement and nutritional status.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Diflunisal

Condition Name

Condition Name for Diflunisal
Intervention Trials
Familial Amyloid Polyneuropathy 1
Bipolar Disorder 1
Atrial Fibrillation 1
Amyloidosis 1
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Condition MeSH

Condition MeSH for Diflunisal
Intervention Trials
Amyloidosis 2
Amyloid Neuropathies, Familial 2
Amyloidosis, Familial 1
Atrial Fibrillation 1
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Clinical Trial Locations for Diflunisal

Trials by Country

Trials by Country for Diflunisal
Location Trials
United States 4
United Kingdom 2
Sweden 2
Japan 1
Italy 1
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Trials by US State

Trials by US State for Diflunisal
Location Trials
Texas 1
New York 1
Minnesota 1
Massachusetts 1
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Clinical Trial Progress for Diflunisal

Clinical Trial Phase

Clinical Trial Phase for Diflunisal
Clinical Trial Phase Trials
Phase 4 2
Phase 2/Phase 3 1
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Diflunisal
Clinical Trial Phase Trials
Completed 4
Suspended 1
Recruiting 1
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Clinical Trial Sponsors for Diflunisal

Sponsor Name

Sponsor Name for Diflunisal
Sponsor Trials
Umeå University 1
The University of Texas Health Science Center, Houston 1
Boston University 1
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Sponsor Type

Sponsor Type for Diflunisal
Sponsor Trials
Other 10
NIH 1
U.S. Fed 1
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