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Last Updated: January 26, 2023

CLINICAL TRIALS PROFILE FOR DEXAMETHASONE INTENSOL


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All Clinical Trials for Dexamethasone Intensol

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00075725 ↗ Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia Completed National Cancer Institute (NCI) Phase 3 2003-12-29 This randomized phase III trial is studying dexamethasone to see how well it works compared to prednisone during induction therapy. This trial is also studying methotrexate and leucovorin calcium to see how well they work compared to methotrexate alone during maintenance therapy in treating patients with newly diagnosed acute lymphoblastic leukemia (ALL). Drugs used in chemotherapy, such as dexamethasone, prednisone, methotrexate, and leucovorin calcium, work in different ways to stop cancer cells from dividing so they stop growing or die. Giving more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating acute lymphoblastic leukemia.
NCT00075725 ↗ Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia Completed Children's Oncology Group Phase 3 2003-12-29 This randomized phase III trial is studying dexamethasone to see how well it works compared to prednisone during induction therapy. This trial is also studying methotrexate and leucovorin calcium to see how well they work compared to methotrexate alone during maintenance therapy in treating patients with newly diagnosed acute lymphoblastic leukemia (ALL). Drugs used in chemotherapy, such as dexamethasone, prednisone, methotrexate, and leucovorin calcium, work in different ways to stop cancer cells from dividing so they stop growing or die. Giving more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating acute lymphoblastic leukemia.
NCT00098475 ↗ Lenalidomide and Dexamethasone With or Without Thalidomide in Treating Patients With Multiple Myeloma Active, not recruiting National Cancer Institute (NCI) Phase 3 2004-10-26 This randomized phase III trial studies lenalidomide and low-dose dexamethasone to see how well it works compared to lenalidomide and standard-dose dexamethasone, given with or without thalidomide, in treating patients with multiple myeloma. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Lenalidomide and thalidomide may also stop the growth of multiple myeloma by blocking blood flow to the cancer. Drugs used in chemotherapy, such as dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving lenalidomide, thalidomide, and dexamethasone together may kill more cancer cells.
NCT00103285 ↗ Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Completed National Cancer Institute (NCI) Phase 3 2005-04-11 This randomized phase III trial is studying different combination chemotherapy regimens and comparing how well they work in treating patients with newly diagnosed acute lymphoblastic leukemia. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells.
NCT00103285 ↗ Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Completed Children's Oncology Group Phase 3 2005-04-11 This randomized phase III trial is studying different combination chemotherapy regimens and comparing how well they work in treating patients with newly diagnosed acute lymphoblastic leukemia. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Dexamethasone Intensol

Condition Name

Condition Name for Dexamethasone Intensol
Intervention Trials
Recurrent Plasma Cell Myeloma 17
Refractory Plasma Cell Myeloma 15
Acute Lymphoblastic Leukemia 15
Untreated Adult Acute Lymphoblastic Leukemia 11
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Condition MeSH

Condition MeSH for Dexamethasone Intensol
Intervention Trials
Leukemia 33
Leukemia, Lymphoid 31
Precursor Cell Lymphoblastic Leukemia-Lymphoma 31
Neoplasms, Plasma Cell 30
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Clinical Trial Locations for Dexamethasone Intensol

Trials by Country

Trials by Country for Dexamethasone Intensol
Location Trials
Canada 104
Australia 57
New Zealand 24
Puerto Rico 12
Switzerland 6
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Trials by US State

Trials by US State for Dexamethasone Intensol
Location Trials
Texas 42
California 35
Minnesota 35
Georgia 30
Ohio 29
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Clinical Trial Progress for Dexamethasone Intensol

Clinical Trial Phase

Clinical Trial Phase for Dexamethasone Intensol
Clinical Trial Phase Trials
Phase 3 18
Phase 2/Phase 3 3
Phase 2 35
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Clinical Trial Status

Clinical Trial Status for Dexamethasone Intensol
Clinical Trial Phase Trials
Recruiting 39
Active, not recruiting 17
Not yet recruiting 13
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Clinical Trial Sponsors for Dexamethasone Intensol

Sponsor Name

Sponsor Name for Dexamethasone Intensol
Sponsor Trials
National Cancer Institute (NCI) 68
M.D. Anderson Cancer Center 17
Mayo Clinic 9
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Sponsor Type

Sponsor Type for Dexamethasone Intensol
Sponsor Trials
NIH 68
Other 68
Industry 20
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