Desoximetasone Spray 0.05%, 0.25%; Dose Ranging Study
Completed
Taro Pharmaceuticals USA
Phase 2
2009-11-01
The objectives of this study are to evaluate the efficacy and safety of two dosing regimens
of desoximetasone 0.05% and 0.25% topical sprays as compared to a vehicle spray in patients
with moderate to severe plaque psoriasis.
Desoximetasone Spray 0.25%, Hypothalamic Pituitary Adrenal (HPA) Axis Study
Completed
Taro Pharmaceuticals USA
Phase 2
2010-02-01
The objective of this study is to evaluate the potential of desoximetasone 0.25% topical
spray to suppress HPA axis function. The potential for adrenal suppression will be assessed
following multiple dosing with Desoximetasone 0.25% Topical Spray in patients with moderate
to severe plaque psoriasis. The secondary objectives are to evaluate the efficacy parameters
and to evaluate the adverse event (AE) profile.
Effects of Desoximetasone Spray 0.25% in Patients With Moderate to Severe Plaque Psoriasis
Completed
Taro Pharmaceuticals USA
Phase 3
2010-08-01
The objective of this study is to demonstrate that desoximetasone 0.25% topical spray is
effective for the treatment of patients with moderate to severe plaque psoriasis.
Adrenal Suppression and Pharmacokinetics of Topicort® Spray, 0.25% in Pediatric Patients With Plaque Psoriasis
Completed
Taro Pharmaceuticals USA
Phase 4
2015-01-23
The objective of this study is to evaluate the potential of Topicort® (desoximetasone)
Topical Spray, 0.25% to suppress hypothalmic pituitary adrenal axis function. The secondary
objectives are to evaluate the efficacy parameters, pharmacokinetics and adverse event
profile.
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