Administration of Oral Contraceptives at Different Times of the Follicular Phase of the Menstrual Cycle
Completed
Canadian Institutes of Health Research (CIHR)
N/A
2002-02-01
We hypothesize that administration of OCs at varying follicular diameters will provide an
appropriate model for the study of follicular atresia in women. Clinically, we hypothesize
that the administration on OCs at different stages of the follicular phase will result in
markedly different patterns of follicular development and/or atresia.
Administration of Oral Contraceptives at Different Times of the Follicular Phase of the Menstrual Cycle
Completed
University of Saskatchewan
N/A
2002-02-01
We hypothesize that administration of OCs at varying follicular diameters will provide an
appropriate model for the study of follicular atresia in women. Clinically, we hypothesize
that the administration on OCs at different stages of the follicular phase will result in
markedly different patterns of follicular development and/or atresia.
Oral Versus Patch Hormonal Contraceptive Effects on Metabolism, Clotting, Inflammatory Factors and Vascular Reactivity
Unknown status
Ortho-McNeil Pharmaceutical
Phase 2
2007-02-01
The purpose of this study is to compare the effects of oral versus patch administration of
hormonal contraception on hormone sensitive proteins such as lipoproteins, clotting factors
and inflammatory proteins as well as blood sugar and insulin levels, antioxidant status and
flow-mediated dilation of arm and forearm vessels. The hypothesis is that oral administration
of contraceptive hormones will result in higher plasma levels of estrogen sensitive proteins
originating from the liver while patch administration of contraceptive hormones will result
in greater systemic effects of estrogen on vascular reactivity and antioxidant status.
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