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Generated: December 16, 2018

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CLINICAL TRIALS PROFILE FOR DEOXYCHOLIC ACID

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Clinical Trials for Deoxycholic Acid

Trial ID Title Status Sponsor Phase Summary
NCT00422188 Deoxycholic Acid Injection for the Treatment of Superficial Lipomas Completed Kythera Biopharmaceuticals Phase 1 The purpose of this research is to compare the safety and effectiveness of 4 different concentrations of deoxycholic acid injection against a placebo in the treatment of superficial lipomas.
NCT00608842 Phase 2 Study for the Treatment of Superficial Lipomas Completed Kythera Biopharmaceuticals Phase 2 The purpose of this research is to compare the safety and effectiveness of 3 different concentrations of deoxycholic acid for injection against a placebo in the treatment of superficial lipomas.
NCT00618618 Phase 2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat Completed Kythera Biopharmaceuticals Phase 2 Phase 2 trial to evaluate the safety and potential efficacy of one concentration of deoxycholic acid injection, given in three dosing paradigms, compared to placebo for the reduction of submental fat (fat beneath the chin).
NCT00618722 Phase 1-2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat Completed Kythera Biopharmaceuticals Phase 1/Phase 2 To evaluate the safety and potential efficacy of deoxycholic acid injection compared to placebo for the reduction of submental fat (fat below the chin).
NCT00858858 Clinical Studies on Bile Acids in Barrett's Esophagus Completed VA Office of Research and Development N/A This study has two major goals: 1. To determine the effects of bile salts on causing DNA injury and activating signaling pathways that promote growth in cells from the esophagus of patients who have gastroesophageal reflux disease (GERD) 2. To determine whether changes in bile composition induced by treating patients with a bile salt called ursodeoxycholic acid (UDCA) can alter DNA injury, signaling pathway activation and other types of damage in cells from the esophagus of patients who have GERD.
NCT01032889 Deoxycholic Acid Injection Submental Fat (SMF) Magnetic Resonance Imaging (MRI) and Subject-reported Outcome Measures Study Completed Kythera Biopharmaceuticals Phase 2 Evaluation of the safety, tolerability and efficacy of deoxycholic acid injection in the reduction of submental fat (fat below the chin).
NCT01294644 Evaluation of Safety and Efficacy of Deoxycholic Acid Injection (ATX-101) in the Reduction of Submental Fat Completed Bayer Phase 3 To evaluate the safety and efficacy of deoxycholic acid injection in the reduction of submental fat (fat below the chin).
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Deoxycholic Acid

Condition Name

Condition Name for Deoxycholic Acid
Intervention Trials
Moderate or Severe Submental Fullness 9
Submental Fat 3
Lipoma 2
Healthy Volunteers 2
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Condition MeSH

Condition MeSH for Deoxycholic Acid
Intervention Trials
Lipoma 2
Barrett Esophagus 1
Diarrhea 1
Gastroesophageal Reflux 1
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Clinical Trial Locations for Deoxycholic Acid

Trials by Country

Trials by Country for Deoxycholic Acid
Location Trials
United States 85
Canada 10
United Kingdom 5
Germany 3
Australia 3
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Trials by US State

Trials by US State for Deoxycholic Acid
Location Trials
California 9
New York 6
Florida 6
Illinois 6
Texas 5
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Clinical Trial Progress for Deoxycholic Acid

Clinical Trial Phase

Clinical Trial Phase for Deoxycholic Acid
Clinical Trial Phase Trials
Phase 3 9
Phase 2 3
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Deoxycholic Acid
Clinical Trial Phase Trials
Completed 15
Not yet recruiting 1
Recruiting 1
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Clinical Trial Sponsors for Deoxycholic Acid

Sponsor Name

Sponsor Name for Deoxycholic Acid
Sponsor Trials
Kythera Biopharmaceuticals 14
Bayer 2
VA Office of Research and Development 1
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Sponsor Type

Sponsor Type for Deoxycholic Acid
Sponsor Trials
Industry 16
Other 2
U.S. Fed 1
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