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CLINICAL TRIALS PROFILE FOR DEFINITY
Clinical Trials for Definity
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00162058 | A Phase II Study of DMP 115 to Assess Focal Liver Lesions | Completed | Lantheus Medical Imaging | Phase 2 | 2004-03-01 | To determine the optimal dose of DMP 115 to image liver lesions and to assess whether contrast can improve the detection of focal liver lesions. |
| NCT00162370 | A Study of Stress Echocardiography in Post-Menopausal Women at Risk for Coronary Disease | Completed | Lantheus Medical Imaging | Phase 4 | 2004-04-01 | The study is designed to see if stress echocardiography can be used as a screening exam in peri-, or post-menopausal women with a risk of developing of coronary artery disease and experiencing future cardiac events. |
| NCT00239525 | 3-D Transcranial Ultrasound Analysis Study | Completed | Duke University | N/A | 2006-05-01 | The purpose of this study is to investigate real time 3-D ultrasound imaging of the brain for the diagnosis and evaluation of stroke. |
| NCT00401687 | DMP115 in Patients With an Ejection Fraction Between 25%-40% to Evaluate the Use of Contrast Echocardiography to Assess Heart Function | Completed | Lantheus Medical Imaging | Phase 4 | 2006-07-01 | The purpose of this clinical research study is to demonstrate the ability of Definity® enhanced versus unenhanced cardiac ultrasound to improve the accuracy and reproducibility of left ventricular ejection fraction (EF) when compared to magnetic resonance imaging (MRI). |
| NCT00507806 | Microbubble-Enhanced Clotbust Treatment of Acute Ischemic Stroke | Terminated | ImaRx Therapeutics | Phase 1/Phase 2 | 2005-03-01 | The study is designed to examine the safety, tolerability, and activity of a combination of microbubbles (perflutren lipid microsphere [Definity®]) and continuous monitoring with 2 MHz transcranial Doppler ultrasound (TCD) as an adjunctive therapy to tissue plasminogen activator (tPA) treatment in subjects with acute ischemic stroke. |
| NCT00580580 | Detection of Coronary Stenosis With Intravenous Microbubbles | Withdrawn | University of Nebraska | N/A | 2012-02-01 | To detect coronary artery disease by both coronary and carotid artery imaging and myocardial perfusion imaging using a new low mechanical index real time system. |
| NCT00584402 | Contrast Sonography for Evaluation of Liver Tumors Prior to Radiofrequency Ablation | Completed | University of California, Davis | N/A | 2007-04-01 | The purpose of this study is to determine the efficacy of the Definity (perflutren lipid microsphere Injectable Suspension) ultrasound contrast agent in identifying small tumors (hepatomas & metastases) within the liver. Primary objective: To estimate the increase in conspicuity of small intrahepatic tumors with contrast-enhanced sonography Secondary Objectives: To estimate the effect of tumor type, size, location and depth on the conspicuity of small tumors on contrast-enhanced sonography |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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