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Last Updated: October 20, 2019

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CLINICAL TRIALS PROFILE FOR DEFINITY

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Clinical Trials for Definity

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00162058 A Phase II Study of DMP 115 to Assess Focal Liver Lesions Completed Lantheus Medical Imaging Phase 2 2004-03-01 To determine the optimal dose of DMP 115 to image liver lesions and to assess whether contrast can improve the detection of focal liver lesions.
NCT00162370 A Study of Stress Echocardiography in Post-Menopausal Women at Risk for Coronary Disease Completed Lantheus Medical Imaging Phase 4 2004-04-01 The study is designed to see if stress echocardiography can be used as a screening exam in peri-, or post-menopausal women with a risk of developing of coronary artery disease and experiencing future cardiac events.
NCT00239525 3-D Transcranial Ultrasound Analysis Study Completed Duke University N/A 2006-05-01 The purpose of this study is to investigate real time 3-D ultrasound imaging of the brain for the diagnosis and evaluation of stroke.
NCT00401687 DMP115 in Patients With an Ejection Fraction Between 25%-40% to Evaluate the Use of Contrast Echocardiography to Assess Heart Function Completed Lantheus Medical Imaging Phase 4 2006-07-01 The purpose of this clinical research study is to demonstrate the ability of Definity® enhanced versus unenhanced cardiac ultrasound to improve the accuracy and reproducibility of left ventricular ejection fraction (EF) when compared to magnetic resonance imaging (MRI).
NCT00507806 Microbubble-Enhanced Clotbust Treatment of Acute Ischemic Stroke Terminated ImaRx Therapeutics Phase 1/Phase 2 2005-03-01 The study is designed to examine the safety, tolerability, and activity of a combination of microbubbles (perflutren lipid microsphere [Definity®]) and continuous monitoring with 2 MHz transcranial Doppler ultrasound (TCD) as an adjunctive therapy to tissue plasminogen activator (tPA) treatment in subjects with acute ischemic stroke.
NCT00580580 Detection of Coronary Stenosis With Intravenous Microbubbles Withdrawn University of Nebraska N/A 2012-02-01 To detect coronary artery disease by both coronary and carotid artery imaging and myocardial perfusion imaging using a new low mechanical index real time system.
NCT00584402 Contrast Sonography for Evaluation of Liver Tumors Prior to Radiofrequency Ablation Completed University of California, Davis N/A 2007-04-01 The purpose of this study is to determine the efficacy of the Definity (perflutren lipid microsphere Injectable Suspension) ultrasound contrast agent in identifying small tumors (hepatomas & metastases) within the liver. Primary objective: To estimate the increase in conspicuity of small intrahepatic tumors with contrast-enhanced sonography Secondary Objectives: To estimate the effect of tumor type, size, location and depth on the conspicuity of small tumors on contrast-enhanced sonography
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Definity

Condition Name

Condition Name for Definity
Intervention Trials
Coronary Artery Disease 3
Breast Cancer 3
Kidney Cancer 3
Cystic Kidney Disease 2
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Condition MeSH

Condition MeSH for Definity
Intervention Trials
Heart Diseases 5
Carcinoma, Renal Cell 5
Renal Insufficiency, Chronic 4
Kidney Diseases 4
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Clinical Trial Locations for Definity

Trials by Country

Trials by Country for Definity
Location Trials
United States 70
Canada 2
United Kingdom 1
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Trials by US State

Trials by US State for Definity
Location Trials
North Carolina 9
Pennsylvania 8
Minnesota 7
Texas 6
California 5
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Clinical Trial Progress for Definity

Clinical Trial Phase

Clinical Trial Phase for Definity
Clinical Trial Phase Trials
Phase 4 10
Phase 3 4
Phase 2 9
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Clinical Trial Status

Clinical Trial Status for Definity
Clinical Trial Phase Trials
Completed 15
Not yet recruiting 11
Recruiting 9
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Clinical Trial Sponsors for Definity

Sponsor Name

Sponsor Name for Definity
Sponsor Trials
Lantheus Medical Imaging 17
National Institutes of Health (NIH) 4
Thomas Jefferson University 4
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Sponsor Type

Sponsor Type for Definity
Sponsor Trials
Other 57
Industry 24
NIH 10
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