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Last Updated: September 21, 2021

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CLINICAL TRIALS PROFILE FOR DEFINITY

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All Clinical Trials for Definity

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00162058 ↗ A Phase II Study of DMP 115 to Assess Focal Liver Lesions Completed Lantheus Medical Imaging Phase 2 2004-03-01 To determine the optimal dose of DMP 115 to image liver lesions and to assess whether contrast can improve the detection of focal liver lesions.
NCT00162370 ↗ A Study of Stress Echocardiography in Post-Menopausal Women at Risk for Coronary Disease Completed Lantheus Medical Imaging Phase 4 2004-04-01 The study is designed to see if stress echocardiography can be used as a screening exam in peri-, or post-menopausal women with a risk of developing of coronary artery disease and experiencing future cardiac events.
NCT00239525 ↗ 3-D Transcranial Ultrasound Analysis Study Completed Duke University N/A 2006-05-01 The purpose of this study is to investigate real time 3-D ultrasound imaging of the brain for the diagnosis and evaluation of stroke.
NCT00401687 ↗ DMP115 in Patients With an Ejection Fraction Between 25%-40% to Evaluate the Use of Contrast Echocardiography to Assess Heart Function Completed Lantheus Medical Imaging Phase 4 2006-07-01 The purpose of this clinical research study is to demonstrate the ability of Definity┬« enhanced versus unenhanced cardiac ultrasound to improve the accuracy and reproducibility of left ventricular ejection fraction (EF) when compared to magnetic resonance imaging (MRI).
NCT00507806 ↗ Microbubble-Enhanced Clotbust Treatment of Acute Ischemic Stroke Terminated ImaRx Therapeutics Phase 1/Phase 2 2005-03-01 The study is designed to examine the safety, tolerability, and activity of a combination of microbubbles (perflutren lipid microsphere [Definity┬«]) and continuous monitoring with 2 MHz transcranial Doppler ultrasound (TCD) as an adjunctive therapy to tissue plasminogen activator (tPA) treatment in subjects with acute ischemic stroke.
NCT00580580 ↗ Detection of Coronary Stenosis With Intravenous Microbubbles Withdrawn University of Nebraska N/A 2012-02-01 To detect coronary artery disease by both coronary and carotid artery imaging and myocardial perfusion imaging using a new low mechanical index real time system.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Definity

Condition Name

Condition Name for Definity
Intervention Trials
Breast Cancer 4
Coronary Artery Disease 3
Kidney Cancer 3
Cardiac Disease 2
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Condition MeSH

Condition MeSH for Definity
Intervention Trials
Heart Diseases 5
Carcinoma, Renal Cell 5
Renal Insufficiency, Chronic 4
Kidney Diseases 4
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Clinical Trial Locations for Definity

Trials by Country

Trials by Country for Definity
Location Trials
United States 73
Canada 2
United Kingdom 1
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Trials by US State

Trials by US State for Definity
Location Trials
Pennsylvania 10
North Carolina 10
Minnesota 7
Texas 6
California 5
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Clinical Trial Progress for Definity

Clinical Trial Phase

Clinical Trial Phase for Definity
Clinical Trial Phase Trials
Phase 4 10
Phase 3 4
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Definity
Clinical Trial Phase Trials
Completed 15
Not yet recruiting 12
Recruiting 11
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Clinical Trial Sponsors for Definity

Sponsor Name

Sponsor Name for Definity
Sponsor Trials
Lantheus Medical Imaging 17
National Cancer Institute (NCI) 5
UNC Lineberger Comprehensive Cancer Center 5
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Sponsor Type

Sponsor Type for Definity
Sponsor Trials
Other 60
Industry 24
NIH 11
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Serving leading biopharmaceutical companies globally:

Medtronic
Harvard Business School
Baxter
McKinsey
Mallinckrodt
Dow

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