Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer
Active, not recruiting
GlaxoSmithKline
Phase 1/Phase 2
2013-07-19
This phase I/II trial studies the side effects and the best dose of uprosertib when given
together with dabrafenib and trametinib and to see how well they work in treating patients
with stage IIIC-IV cancer. Uprosertib, dabrafenib, and trametinib may stop the growth of
tumor cells by blocking some of the enzymes needed for cell growth. Giving uprosertib with
dabrafenib and trametinib may be a better treatment for cancer.
Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer
Active, not recruiting
Novartis Pharmaceuticals
Phase 1/Phase 2
2013-07-19
This phase I/II trial studies the side effects and the best dose of uprosertib when given
together with dabrafenib and trametinib and to see how well they work in treating patients
with stage IIIC-IV cancer. Uprosertib, dabrafenib, and trametinib may stop the growth of
tumor cells by blocking some of the enzymes needed for cell growth. Giving uprosertib with
dabrafenib and trametinib may be a better treatment for cancer.
Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer
Active, not recruiting
National Cancer Institute (NCI)
Phase 1/Phase 2
2013-07-19
This phase I/II trial studies the side effects and the best dose of uprosertib when given
together with dabrafenib and trametinib and to see how well they work in treating patients
with stage IIIC-IV cancer. Uprosertib, dabrafenib, and trametinib may stop the growth of
tumor cells by blocking some of the enzymes needed for cell growth. Giving uprosertib with
dabrafenib and trametinib may be a better treatment for cancer.
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