Exploratory Clinical Trial of Safety and Efficacy of Daily Application of Topical Dutasteride in Men With Androgenic Alopecia.
Recruiting
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Phase 2
2022-09-29
Alopecia is a disorder that involves the loss of hair from the body. The causes of hair loss
can be multiple, but in all cases this loss causes a lot of discomfort to patients for
aesthetic and psychological reasons, especially in the female population.This study is going
to focus on the topical use of dutasteride in the treatment of men with androgenic alopecia
using a new formulation, as an emulsion, capable of transporting this drug to the different
structures of the pilosebaceous unit.
"REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk
Completed
GlaxoSmithKline
Phase 3
2003-03-01
This 4-year study will compare how safe and effective an oral investigational medicine is
(compared to placebo) in preventing the development of prostate cancer in men that are
defined by the study entrance criteria as being at an increased risk for prostate cancer.
Study visits to the clinic will occur every 6 months for up to 4 years (10 clinic visits),
and a prostate biopsy will be performed at 2 and 4 years of treatment.
Effect Of Dutasteride On Intraprostatic Dihydrotestosterone (DHT) Levels
Completed
GlaxoSmithKline
Phase 4
2003-10-01
This study is being done to determine how much certain hormone levels in the prostate
decrease when a patient takes dutasteride 0.5mg daily for 3 months prior to TURP. Male
patients at least 50 years old willing to take either dutasteride or a placebo (dummy pill)
once daily by mouth for 3 months prior to having a surgery to reduce the size of their
prostate. During the surgery, very small pieces of the prostate that are removed will be
tested to see how much dihydrotestosterone and testosterone (male hormones) are in the
tissue.
The Effect of 5-Alpha Reductase on Testosterone in Men
Unknown status
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Phase 3
2003-08-01
The enzyme 5-alpha reductase is present in small amounts in muscle and converts testosterone
to dihydrotestosterone (DHT). Testosterone affects lean body tissue, muscle size, muscle
strength, and sexual function in men. This study will evaluate how 5-alpha reductase
influences the effects of testosterone in young healthy men.
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