Opioid Based Analgesia vs Non-opioid Analgesia for Oocyte Retrieval Procedure
Not yet recruiting
Tel-Aviv Sourasky Medical Center
N/A
2021-11-01
It is unclear whether routine addition of opioids for analgesia during minor gynecological
procedures is beneficial. In this single-center randomized single-blinded trial, the
investigators aim to test the primary hypothesis that opioid-sparing anesthesia regimen
including intravenous acetaminophen is non-inferior to a similar anesthesia regimen
containing fentanyl in providing postoperative analgesia in women recovering from oocyte
retrieval procedures for in vitro fertilization. The investigators also aim to assess the
difference in incidence of patient-reported opioid related adverse-effects between the two
groups, time to discharge from the post-anesthesia care unit and postoperative rescue
analgesia requirements. If we demonstrate no clinically important difference between the two
interventions, clinicians may be able to substantially reduce the amount of opioids
administered to patients undergoing minor ambulatory procedures, and potentially decrease the
associated opioid related adverse effects.
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