Last Updated: August 9, 2026

CLINICAL TRIALS PROFILE FOR DEFENCATH

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All Clinical Trials for DEFENCATH

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT06714864 ↗	Open-Label Study to Assess Safety and Time to Catheter-related Bloodstream Infections (CRBSI) in Subjects From Birth to < 18 Years of Age	RECRUITING	CorMedix	PHASE4	2025-07-08	This study is a post-marketing approval requirement to assess the safety and time to Catheter-related Bloodstream Infections (CRBSI) of DefenCath in pediatric population (birth to less than 18 years of age) who are on chronic HD for kidney failure.
NCT06822426 ↗	Comparing The Safety And Efficacy Of DEFENCATH In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)	RECRUITING	CorMedix	PHASE3	2025-05-14	This is a Phase 3, randomized, double-blind, controlled, adaptive, 2-arm, multicenter study to demonstrate the efficacy and safety of DefenCath in adult participants receiving home Total Parenteral Nutrition (TPN) via Central Venous Catheter (CVC) compared with heparin.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for DEFENCATH

Condition Name

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Condition Name for DEFENCATH
Intervention	Trials
Catheter-Related Infections	1
Central Line Associated Blood Stream Infections (CLABSI)	1
[disabled in preview]	1
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Condition MeSH

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Condition MeSH for DEFENCATH
Intervention	Trials
Catheter-Related Infections	1
[disabled in preview]	1
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Clinical Trial Locations for DEFENCATH

Trials by Country

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Trials by Country for DEFENCATH
Location	Trials
United States	14
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Trials by US State

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Trials by US State for DEFENCATH
Location	Trials
Tennessee	1
Rhode Island	1
Pennsylvania	1
Ohio	1
North Carolina	1
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Clinical Trial Progress for DEFENCATH

Clinical Trial Phase

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Clinical Trial Phase for DEFENCATH
Clinical Trial Phase	Trials
PHASE4	1
PHASE3	1
[disabled in preview]	0
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Clinical Trial Status

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Clinical Trial Status for DEFENCATH
Clinical Trial Phase	Trials
RECRUITING	2
[disabled in preview]	0
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Clinical Trial Sponsors for DEFENCATH

Sponsor Name

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Sponsor Name for DEFENCATH
Sponsor	Trials
CorMedix	2
[disabled in preview]	0
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Sponsor Type

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Sponsor Type for DEFENCATH
Sponsor	Trials
INDUSTRY	2
[disabled in preview]	0
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