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Last Updated: May 27, 2022

CLINICAL TRIALS PROFILE FOR CYANOCOBALAMIN


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All Clinical Trials for Cyanocobalamin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00004495 ↗ Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis Completed Georgetown University N/A 1999-06-01 OBJECTIVES: I. Compare the efficacy of two doses of folic acid in normalizing plasma total homocysteine concentration in patients with end stage renal disease receiving regular hemodialysis therapy resulting in hyperhomocysteinemia. II. Determine the requirement of co-supplementation with extra pyridoxine (vitamin B6) and cyanocobalamin (vitamin B12) daily in these patients. III. Assess the safety and tolerability of this therapy in these patients.
NCT00004734 ↗ Vitamin Therapy for Prevention of Stroke Completed National Institute of Neurological Disorders and Stroke (NINDS) Phase 3 1996-09-01 A stroke occurs when part of the brain is damaged from lack of normal blood supply. This may result in difficulty with feeling, speech, muscle strength or coordination, movement, thinking, or other brain functions. Having a stroke increases the risk of another stroke occurring in the future. Higher blood levels of a natural chemical known as homocysteine may contribute to hardening of the arteries in the brain or heart and increase the risk of stroke or heart attack. Folic acid, vitamin B6 (pyridoxine), and vitamin B12 (cyanocobalamin) may lower blood levels of homocysteine and reduce the risk of having another stroke or a heart attack.
NCT00032435 ↗ Homocysteine Study (HOST) Completed Abbott Diagnostics Division Phase 3 2001-05-01 The primary objective of this study is to test the hypothesis that administration of folate, pyridoxine (vitamin B6) and cyanocobalamin (vitamin B12) in high doses to patients with advanced chronic renal failure or end stage renal disease and abnormally high plasma homocysteine levels will lower the homocysteine levels and the death rate compared to patients who receive placebo. The secondary objective is to test the hypothesis that intake of the vitamins compared to placebo decreases the incidence of myocardial infarction, disabling stroke, and amputation of a lower extremity and, in hemodialysis patients, thrombosis of the vascular access.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Cyanocobalamin

Condition Name

Condition Name for Cyanocobalamin
Intervention Trials
Vitamin B12 Deficiency 3
End Stage Renal Disease 2
Anaemia 2
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Condition MeSH

Condition MeSH for Cyanocobalamin
Intervention Trials
Vitamin B 12 Deficiency 5
Lymphoma 4
Lymphoma, T-Cell 3
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Clinical Trial Locations for Cyanocobalamin

Trials by Country

Trials by Country for Cyanocobalamin
Location Trials
United States 195
India 9
Hungary 7
France 5
Argentina 5
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Trials by US State

Trials by US State for Cyanocobalamin
Location Trials
Texas 12
New York 12
Illinois 11
California 11
Pennsylvania 10
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Clinical Trial Progress for Cyanocobalamin

Clinical Trial Phase

Clinical Trial Phase for Cyanocobalamin
Clinical Trial Phase Trials
Phase 4 3
Phase 3 5
Phase 2 18
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Clinical Trial Status

Clinical Trial Status for Cyanocobalamin
Clinical Trial Phase Trials
Completed 29
Terminated 3
Recruiting 2
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Clinical Trial Sponsors for Cyanocobalamin

Sponsor Name

Sponsor Name for Cyanocobalamin
Sponsor Trials
National Cancer Institute (NCI) 8
Spectrum Pharmaceuticals, Inc 7
Acrotech Biopharma LLC 5
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Sponsor Type

Sponsor Type for Cyanocobalamin
Sponsor Trials
Other 32
Industry 19
NIH 9
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