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Last Updated: October 17, 2019

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CLINICAL TRIALS PROFILE FOR CRISABOROLE

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Clinical Trials for Crisaborole

Trial ID Title Status Sponsor Phase Start Date Summary
NCT03233529 Crisaborole Ointment 2% Skin Biomarker Biopsy Study in Atopic Dermatitis Not yet recruiting Pfizer Phase 2 2017-07-31 This study is being conducted to characterize the mechanism of action of crisaborole ointment 2%, by evaluation of efficacy and changes in key skin biomarkers in atopic dermatitis (AD) lesions treated with crisaborole ointment 2% over vehicle, in subjects with mild to moderate AD. Two identified AD skin lesions for each subject will be treated for the first 15 days, one with crisaborole ointment 2% and one with vehicle, in a blinded manner, and biopsies for biomarker analysis will be performed on the lesions. Following completion of the blinded treatment period, subjects will start the 28 day open label period during which all AD affected skin lesions will be treated with crisaborole ointment 2% twice daily.
NCT03260595 A Study of Crisaborole Ointment 2% in Adult Japanese Healthy Subjects and Adult Japanese Subjects With Mild To Moderate Atopic Dermatit Not yet recruiting Pfizer Phase 1 2017-09-24 This is a Phase 1 parallel-cohort study of crisaborole ointment 2% to evaluate the skin irritation potential in adult Japanese healthy subjects in Cohort 1, and to evaluate the safety, tolerability and PK in adult Japanese subjects with mild to moderate AD in Cohort 2.
NCT03351114 Pilot Study Evaluating the Efficacy of a Topical PDE4 Inhibitor for Morphea Not yet recruiting Pfizer Phase 2 2018-01-01 This is a pilot study to determine the safety and clinical efficacy of crisaborole 2% ointment in the treatment of morphea.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Crisaborole

Condition Name

Condition Name for Crisaborole
Intervention Trials
Atopic Dermatitis 8
Dermatitis, Atopic 2
Healthy 2
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Condition MeSH

Condition MeSH for Crisaborole
Intervention Trials
Dermatitis 11
Eczema 10
Dermatitis, Atopic 10
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Clinical Trial Locations for Crisaborole

Trials by Country

Trials by Country for Crisaborole
Location Trials
United States 12
Canada 2
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Trials by US State

Trials by US State for Crisaborole
Location Trials
Kentucky 2
Arkansas 2
Illinois 1
Maryland 1
Connecticut 1
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Clinical Trial Progress for Crisaborole

Clinical Trial Phase

Clinical Trial Phase for Crisaborole
Clinical Trial Phase Trials
Phase 4 6
Phase 3 2
Phase 2 3
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Clinical Trial Status

Clinical Trial Status for Crisaborole
Clinical Trial Phase Trials
Not yet recruiting 10
Recruiting 3
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Clinical Trial Sponsors for Crisaborole

Sponsor Name

Sponsor Name for Crisaborole
Sponsor Trials
Pfizer 10
Ann & Robert H Lurie Children's Hospital of Chicago 1
Innovaderm Research Inc. 1
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Sponsor Type

Sponsor Type for Crisaborole
Sponsor Trials
Industry 10
Other 6
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